EEG event related potentials in sustained, focused and divided attention tasks: Potential biomarkers for cognitive impairment in HIV patients

Meghdadi, Amir H.; Berka, Chris; Richard, Christian; Rupp, Greg; Smith, Stephanie D.; Karić, Marija Stevanović; McShea, Kevin; Sones, Emily; Marinković, Ksenija; Marcotte, Thomas D.

doi:10.1016/j.clinph.2020.11.026

Cited by 5 publications

(2 citation statements)

References 84 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…e two groups di ered in frontal ERP only in the time window around 150-180 ms. is wave likely corresponds to the P200 component, whose amplitude is known to negatively correlate with the level of attention (Crowley & Colrain, 2004) and to re ect inhibition of irrelevant information (Meghdadi et al, 2021;Zhao, Zhou, & Fu, 2013). us, more successful word learners were more attentive than others and were better at suppressing irrelevant inputs.…”

Section: Discussionmentioning

confidence: 97%

Psychological and Electrophysiological Correlates of Word Learning Success

Mkrtychian¹,

Kostromina²,

Gnedykh³

et al. 2021

Psych. Rus.

View full text Add to dashboard Cite

Background. A rich vocabulary supports human achievements in socio-economic activities, education, and communication. It is therefore important to clarify the nature of language acquisition as a complex multidimensional process. However, both the psychological and neurophysiological mechanisms underpinning language learning, as well as the links between them, are still poorly understood. Objective. This study aims to explore the psychological and neurophysiological correlates of successful word acquisition in a person’s native language. Design. Thirty adults read sentences with novel nouns, following which the participants’ electroencephalograms were recorded during a word-reading task. Event-related potentials in response to novel words and alpha oscillation parameters (amplitude, variability, and long-range temporal correlation dynamics) were analyzed. Learning outcomes were assessed at the lexical and semantic levels. Psychological variables measured using Amthauer’s test (verbal abilities), BIS/BAS scales (motivation), and the MSTAT-1 (ambiguity tolerance) and alpha oscillation parameters were factored. Results. Better recognition of novel words was related to two factors which had high factor loadings for all measured alpha oscillation parameters, indicating the role of attention networks and respective neural activity for enabling information processing. More successful learners had lower P200 amplitude, which also suggests higher attention-system involvement. Another factor predicted better acquisition of word meanings for less ambiguity-tolerant students, while the factor which pooled logical conceptual thinking ability and persistence in goal-reaching, positively correlated with acquisition of both word forms and meanings. Conclusion. The psychological factors predominantly correlated with word-learning success in semantic tasks, while neurophysiological variables were linked to performance in the recognition task.

show abstract

Section: Discussionmentioning

confidence: 97%

Psychological and Electrophysiological Correlates of Word Learning Success

Mkrtychian¹,

Kostromina²,

Gnedykh³

et al. 2021

Psych. Rus.

View full text Add to dashboard Cite

show abstract

“…[2] EEG images in HIV patients taking efavirenz show a decrease in sleep efficiency with difficulty in starting sleep, an increase in the number of wakes during sleep, and a decrease in the duration of REM sleep. [7,8] The most optimum time to start ARV therapy is CD4 cells between 200-350/mm3. ARV is recommended in patients with pulmonary TB with severe bacterial infection and CD4 < 350/mm3, and in pregnant women with clinical stage CD4 < 350/mm3.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Sleep Quality in Pre-HAART and on HAART HIV Patients

2021

View full text Add to dashboard Cite

Background/aim: People with HIV are often reported to experience poor sleep quality. Factors that can cause poor sleep quality in HIV patients, including the use of ARV therapy. The pathophysiology of poor sleep quality in HIV patients is still unclear. Poor sleep quality is one of the complaints in the late stages of HIV infection, where it is suspected that HIV itself affects the biological center of sleep. This study was aimed to determine the comparison of sleep quality in HIV patients pre-HAART and with HAART more than 1 year. Method: This study uses data collection methods in the form of interviews with samples which will later be presented in the form of analytical observational study. Consecutive data collection on HIV patients before and after ARV therapy who was outpatient at the VCT outpatient clinic Dr. Soetomo General Hospital from June-July 2021. Data analysis using SPSS Version 23 for windows. Results: A total of 40 subjects were divided into HIV pre-HAART and on HAART. From the statistical analysis using SPSS program significant with p= 0.004 (OR 15.5 (95% CI (1.73-139.6)) Conclusion: HIV patients on HAART for more than 1 year are known to have increased 15.5 times the risk of poor sleep quality. Keywords: HIV, HAART, sleep quality.

show abstract