2018
DOI: 10.1016/j.yebeh.2018.09.036
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EEG endophenotypes in autism spectrum disorder

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Cited by 30 publications
(21 citation statements)
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“…Prior studies have linked neurophysiologic abnormalities to developmental outcomes such as in epileptic encephalopathies and autism spectrum disorders (ASDs) [16]. Capal et al recently suggested abnormal EEG patterns, even in the absence of epilepsy, were linked with worse developmental outcomes in children with ASD [22]. Similarly, abnormal EEG patterns have been linked to a number of other genetically defined intellectual and developmental disorders [2325].…”
Section: Discussionmentioning
confidence: 99%
“…Prior studies have linked neurophysiologic abnormalities to developmental outcomes such as in epileptic encephalopathies and autism spectrum disorders (ASDs) [16]. Capal et al recently suggested abnormal EEG patterns, even in the absence of epilepsy, were linked with worse developmental outcomes in children with ASD [22]. Similarly, abnormal EEG patterns have been linked to a number of other genetically defined intellectual and developmental disorders [2325].…”
Section: Discussionmentioning
confidence: 99%
“…The most reliable endophenotypes in ASD fall in following clinical subgroups: hormonal, biochemical, immunological, morphological, neurophysiological/neuroanatomical, neuropsychological, and behavioral [ 124 ]. Studies which have described endophenotypes of ASD are for hyperserotonemia [ 125 ], abnormalities of electroencepalography (EEG) [ 126 ], neuroimaging [ 127 ], head circumference [ 128 ], immunological [ 129 ], and language delay [ 130 ]. Moreover structural brain region pathophysiologies also constitute endophenotypes, for example, white matter [ 131 ], and grey matter [ 132 ].…”
Section: Endophenotypesmentioning
confidence: 99%
“…All the above studies, although with different percentages, seem to indicate that SEAs, even without clinical seizures, can cause permanent negative effects on the brain development, leading to more serious cognitive and/or behavioral deficits [ 37 , 48 ] and provoking severer forms of autism [ 39 ].…”
Section: Seas In Non-epileptic Patients With Asdmentioning
confidence: 99%
“…For instance, Capal et al in their retrospective study found evidence that patients with ASD and SEAs exhibited more impaired adaptive functioning (evaluated through Vineland Adaptive Behavior Scales) compared with normal EEG-ASD group ( p = 0.05) [ 37 ].…”
Section: Seas In Non-epileptic Patients With Asdmentioning
confidence: 99%