EEG Changes in Neonatal Hypoxic Ischemic Encephalopathy

Abstract

Background: Traditional multichannel EEG is an integral part of the evaluation of neonates diagnosed with neonatal hypoxic ischemic encephalopathy (HIE). HIE is well-defined as the clinical appearance of reduced neonatal brain function after asphyxia due to perinatal and/or an antenatal adverse incident. It is prevalence ranging from 1 to 8 per 1000 worldwide. Objectives: To evaluate EEG changes in neonates with hypoxic ischemic encephalopathy. Method:A cross sectional study conducted from Aug. 2018 till June 2019. The patient included ,term neonate with gestational age from (37 to 42 weeks) admitted in Neonatal Care Unit(NCU) in Babylon teaching hospital for maternity and children , with diagnosis of hypoxic Ischemic Encephalopathy(HIE ) . with total number of 47 were enrolled in the study. Full assessment, including: clinical assessment (history and full examination) and electrophysiological (EEG) were done to all Patients. First EEG was done at age ranged from (2 to 7 days) while second EEG was done at age ranged from (21 to 28 days).Result: In this study, first EEG showed that 8 (17.02%) normal EEG and 39 (82.9%) abnormal EEG results, while second EEG was shown that 15 (31.9%) normal EEG, 17 patients get improvement and 7 get worse. This study was shown that, there are a strong significant statistical deference between the EEG background activity in the first week and developmental mile stone, stage of HIE, neurological examination, age of patients and seizure with p value less than 0.05. Conclusion:EEG of neonates with HIE provides early prognostic and objective information.