EEG and event-related potentials in normal aging

Dustman, Robert E.; Shearer, Donald E.; Emmerson, Rita Y.

doi:10.1016/0301-0082(93)90005-d

Cited by 103 publications

(88 citation statements)

References 197 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For studies that observe cortical coupling by means of measuring the coherence between signals from different electrode locations, the common observation is a higher synchronization for older compared to younger subjects (e.g., Dustman et al, 1985Dustman et al, , 1993. Such findings are in general consistent with the notions of functional dedifferentiation with advancing age due to declining neuromodulation (e.g., Li et al, 2005;Ba¨ckman et al, 2006) or a general loss of inhibitory connections Kinsbourne and Hicks, 1978. …”

Section: Aging-related Changes In Brain Structures and Electrophysiolsupporting

confidence: 76%

“…While early reports (Obrist, 1954) led to the suggestion that advancing age is accompanied by power increases in delta and theta frequencies (sometimes referred to as diffuse slowing), other studies reported decrease in low frequency bands, especially for carefully selected highly healthy samples of older adults (e.g., Duffy et al, 1993). More recent reviews therefore describe decreasing power for theta and delta frequencies as indices of normal aging, while increasing slow wave activity is regarded as a sign for pathological aging (e.g., Dustman et al, 1993;Niedermeyer, 1982).…”

Section: Aging-related Changes In Brain Structures and Electrophysiolmentioning

confidence: 99%

“…Nevertheless, various aging related changes for different EEG indices (e.g., spectral power, coherence) have been reported (e.g., Klimesch, 1999) For instance, with respect to EEG spectral frequencies, a common observation is a decrease in overall power with advancing age. For the alpha frequency band, an age-related reduction of the peak frequency is reported from 10.5 Hz in young adulthood up to o8.5 Hz in people above 70 years of age (Dustman et al, 1993;Klimesch, 1999; but also see Duffy et al, 1993 for different conclusions). Such changes are typically accompanied by increasing power in higher frequencies (i.e., beta and gamma).…”

Section: Aging-related Changes In Brain Structures and Electrophysiolmentioning

confidence: 99%

See 2 more Smart Citations

Cortical EEG correlates of successful memory encoding: Implications for lifespan comparisons

Werkle‐Bergner

Müller

et al. 2006

Neuroscience & Biobehavioral Reviews

122

View full text Add to dashboard Cite

In the course of their lives, individuals experience a myriad of events. Some of them leave stable traces, and others fade away quickly. Recent advances in functional imaging methods allow researchers to contrast neuronal patterns of remembered against not remembered events at initial encoding. Research on young adults using functional magnetic resonance imaging (fMRI), intracranial, and standard electroencephalographic (EEG) recordings has identified differences between remembered and not remembered items in patterns of medio-temporal and prefrontal brain activity. However, little is known about the ways in which such neuronal patterns of successful encoding evolve across the lifespan as a function of maturation, senescence, and the accumulation of experience. Here, we first review empirical evidence on neuronal correlates of successful memory from middle childhood to old age. Based on the observation that associative and strategic components of episodic memory seem to follow different age gradients, we propose a conceptual framework for predicting age changes in neuronal patterns of successful encoding. r

show abstract

Section: Aging-related Changes In Brain Structures and Electrophysiolsupporting

confidence: 76%

Section: Aging-related Changes In Brain Structures and Electrophysiolmentioning

confidence: 99%

Section: Aging-related Changes In Brain Structures and Electrophysiolmentioning

confidence: 99%

See 1 more Smart Citation

Cortical EEG correlates of successful memory encoding: Implications for lifespan comparisons

Werkle‐Bergner

Müller

et al. 2006

Neuroscience & Biobehavioral Reviews

122

View full text Add to dashboard Cite

show abstract

“…The NCT part B, in which patients have to connect rather than to aging itself. 45 Quantified EEG studies in subjects carefully screened for cognitive disturbances fail to show numbers and letters in consecutive order, has been reported to be more sensitive than the NCT part A, because this test substantial slowing of the EEG with age 46-48 ; only marked EEG changes in patients older than 80 years are described. 49 has an increased attentional load.…”

Section: Neuropsychological Assesment Resultsmentioning

confidence: 99%

The diagnosis of subclinical hepatic encephalopathy in patients with cirrhosis using neuropsychological tests and automated electroencephalogram analysis

Quero¹

1996

Hepatology

View full text Add to dashboard Cite

Hepatic encephalopathy (HE) is a serious complication of Neuropsychological tests used for the assessment of advanced liver disease and refers to neuropsychiatric abnorsubclinical hepatic encephalopathy (SHE) may overdimalities (such as disorders of personality, altered levels of agnose SHE because scores are usually not corrected for consciousness, impairment of intellectual function), and neuage. The aim of this study was to estimate the prevalence romuscular dysfunction (asterixis) because of liver insuffiof SHE using two easy administrable psychometric tests ciency. defects, yet have a normal mental and neurological status on One hundred and thirty-seven consecutive patients global clinical examination. [3][4][5][6][7][8][9][10][11][12][13] The prevalence of this subclin-(mean age 49 years, range 17-77) with cirrhosis without ical hepatic encephalopathy (SHE) has been reported to vary any clinical signs of encephalopathy, were screened for from 30% 13 to 84%, 11 depending on the tests and population SHE. In addition, the Child-Pugh score and the arterial used. blood ammonia were determined. Patients with concur-The neuropsychological defects found in SHE may have a rent use of alcohol, benzodiazepines or anti-epileptics negative effect on patients' daily life. 6,14 In addition, these were excluded.defects are considered to be a preclinical stage of clinical Fifty percent of the patients had an abnormal NCT manifest HE. 4,9,15 In view of the reported high incidence of according to the standard recommended procedure, in SHE in patients with cirrhosis and its possible impact on contrast only 7% of the patients had an abnormal NCT daily life, routine assessment of early stages of HE is recomwhen scores corrected for age were used. Combining the mended, 4,6,9,16 as this syndrome may be fully reversible with results of the spectral EEG and the psychometric tests treatment. 4,[17][18][19][20] However, the extensive neuropsychological corrected for age yielded a higher prevalence of SHE test batteries used in most studies (up to 21 different psycho-(23%) than when each test method was used alone (17% metric tests! 9 ), are not suitable for a fast routine screening vs. 10% abnormal, respectively). Severity of liver disease in an outpatient clinic. Conn 21 suggested to use the Number correlated with the presence of SHE, because the preva-Connection Test (NCT) as a sole psychometric test for quantilence of abnormal tests increased from 14% in Child-fying HE. Other investigators 4,9,12,13,22 have proposed to use a Pugh grade A to 45% in Child-Pugh grade B or C. Age combination of two to three psychometric tests as a diagnostic above 40 years and an elevated blood ammonia level screen for SHE. As neuropsychological performance is known were significant determinants related to an abnormal to be influenced by age, 23,24 education, 24 and repetitive test-EEG. We conclude that the NCT uncorrected for age ing, 21 several investigators have used neurophysiological markedly overdiagnoses SHE and, therefore, should not tools suc...

show abstract

“…The underlying causes for the influence of physical exercise on the P300 ERP are far from clear, although speculation on the sources of these effects can be made. For example, it is straightforward to assume that physical exercise promotes cerebral blood flow (CBF) that could affect EEG measures [3,9,29], but why such physiologic changes would affect specific EEG bands is uncertain [30,31]. However, when a decrease in CBF occurs because of anoxia or hypoxia, an increase in delta and decrease in alpha and beta activities typically are observed [32,33].…”

Section: Resultsmentioning

confidence: 99%

Examination of P300 in Veteran Males: Aging, Physical Activity and Cognitive Processing

et al. 2014

View full text Add to dashboard Cite

EEG and event-related potentials in normal aging

Cited by 103 publications

References 197 publications

Cortical EEG correlates of successful memory encoding: Implications for lifespan comparisons

Cortical EEG correlates of successful memory encoding: Implications for lifespan comparisons

The diagnosis of subclinical hepatic encephalopathy in patients with cirrhosis using neuropsychological tests and automated electroencephalogram analysis

Examination of P300 in Veteran Males: Aging, Physical Activity and Cognitive Processing

Contact Info

Product

Resources

About