Education, Employment, Income, and Marital Status Among Adults Diagnosed With Inflammatory Bowel Diseases During Childhood or Adolescence

El‐Matary, Wael; Dufault, Brenden; Moroz, S. P.; Schellenberg, Jeannine; Bernstein, Çharles N.

doi:10.1016/j.cgh.2016.09.146

Cited by 20 publications

(16 citation statements)

References 26 publications

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“…Some individuals focus on the cognitive task at hand and ignore pain, while others are distracted by pain and perform suboptimally on attention demanding tasks . Given that studies have shown that education, employment, and income are not significantly different between patients with IBD and healthy individuals, it is possible that CD patients, even those in remission, might adopt cognitive strategies to function effectively. Although the investigation of brain changes in CD patients has become an increasing focus of several recent studies to explore brain‐gut interactions, our study specifically demonstrates atypical activation patterns on a cognitive task, indicating that brain changes even in younger patients may resemble age‐related changes seen with healthy aging.…”

Section: Discussionmentioning

confidence: 99%

A Verbal Fluency Task‐Based Brain Activation fMRI Study in Patients with Crohn's Disease in Remission

Nair

Dodd

Rajan

et al. 2019

Journal of Neuroimaging

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BACKGROUND AND PURPOSE In this pilot study, we investigated functional brain activation changes in patients with Crohn's disease (CD) in remission compared to age and gender‐matched healthy controls (HCs). METHODS Data from 20 patients with CD in remission (age range 19‐63 years) and 20 HCs (matched in age and gender) were analyzed. Task functional MRI (fMRI) data were collected while participants performed a cognitive (phonemic verbal fluency) task in the scanner. All participants also performed the same task outside the scanner. RESULTS Task fMRI results showed greater bi‐hemispheric activation in CD patients compared to controls. Because this pattern is commonly reported with normal aging, we performed further analyses to investigate fMRI responses in a subset of the younger CD patients (N = 12, age < = 35 years) compared to matched young HCs (age < = 35 years), and an older cohort of HCs (age > = 50 years). Results showed that task activation patterns were similar between young CD patients and older HCs, and that both groups differed significantly from younger HCs. Activation intensity in specific brain regions for patients was associated with disease duration. CONCLUSIONS These results suggest that CD patients in remission may show accelerated signs of aging in terms of brain responses to a typical cognitive task. Future work with larger sample size will need to replicate these results as well as investigate the influence of factors, such as chronicity of the disease and medication effects on task‐associated brain activation patterns in this patient population.

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Section: Discussionmentioning

confidence: 99%

A Verbal Fluency Task‐Based Brain Activation fMRI Study in Patients with Crohn's Disease in Remission

Nair

Dodd

Rajan

et al. 2019

Journal of Neuroimaging

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“…Educational and employment status evaluated after the 4-year observation period did not significantly vary between our transfer and transition group patients. Although young college students with IBD feel less successful and admitted their class attendance rates to be less regular than their healthy controls [54], IBD patients achieved a diploma or a post-secondary school degree more frequently than their healthy peers and earn more money per annum [55, 56]. Since time of transfer and graduation from school occur at a similar time, transition support may enable more patients to start into a successful work life as an adult.…”

Section: Discussionmentioning

confidence: 99%

Long-term implications of structured transition of adolescents with inflammatory bowel disease into adult health care: a retrospective study

et al. 2019

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Background We aimed to evaluate the long-term clinical and socioeconomic outcome of structured transition care in adolescents with inflammatory bowel disease (IBD). Methods We compared the clinical long-term course of 24 patients with and 11 patients without structured transition care within 24 months before and 24 months after transfer from paediatric to adult health care. Socio-economic parameters and quality of life were assessed by IBD Questionnaire (IBDQ-32) and additional items. Treatment costs were calculated for medication, surgery and hospitalisation. Results The percentage of transfer group patients with an IBD-related intestinal complication was higher compared to the transition group (64% vs. 21%, p = 0.022). We also found a tendency towards a higher number of IBD-related surgery in the transfer group compared to the transition group (46% vs. 13%, p = 0.077). Transfer group patients received higher mean cumulated doses of radiation compared with the transition group (4.2 ± 5.3 mSv vs. 0.01 ± 0.01 mSv, p = 0.036). Delayed puberty was only noted in the transfer group (27%, p = 0.025). Mean expenditures for surgeries and hospitalisation tended to be lower in the transition group compared to transfer group patients (744 ± 630€ vs. 2,691 ± 4,150€, p = 0.050). Sexual life satisfaction was significantly higher ( p = 0.023) and rates of loose bowel movements tended to be lower ( p = 0.053) in the transition group. Conclusions Structured transition of adolescents with IBD from paediatric into adult health care can lead to important clinical and economic benefits. Electronic supplementary material The online version of this article (10.1186/s12876-019-1046-5) contains supplementary material, which is available to authorized users.

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“…Inflammatory bowel disease (IBD), which includes Crohn’s disease (CD) and ulcerative colitis (UC), is a chronic disease that causes varying levels of disability in patients. Because of its chronic relapsing and remitting character, IBD impacts patients throughout their lives [1]. Many patients develop IBD at an early age and therefore it can have considerable effects on employment outcomes [2].…”

Section: Introductionmentioning

confidence: 99%

Overcoming Workplace Disability in IBD Patients: An Observational Study

Paulides¹,

Daker²,

Frampton³

et al. 2020

Inflamm Intest Dis

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Background: Inflammatory Bowel Disease (IBD) can have considerable effects on employment outcomes because of its disabling character. Goals: We aimed to investigate the impact of IBD in the workplace and to better understand the need for accommodations and adaptations. Study: Between November 2017 and March 2018, IBD patients were recruited from outpatient clinics in Christchurch Hospital, New Zealand. The survey assessed employment, the need for workplace accommodations and the difficulty arranging it, insurance, and disability using the item-reduced Inflammatory Bowel Disease Disability Index for self-report (IBD-DI-SR). Data were analyzed using descriptive statistics and multivariate logistic regression modeling. Results: One hundred twenty-three patients were included (response rate 64%), 112 of whom reported that they experienced symptoms while working (60% female, 71% Crohn’s disease, mean age 41.9 years). Ninety-one percent needed at least 1 workplace accommodation when symptoms were most severe. Almost half of the patients who needed an accommodation had difficulty arranging it. The most needed accommodations were time to go to medical appointments (71%) and easy access to a suitable toilet (71%). Being female, having less effective medication, and being distressed were associated with the need for 2 or more accommodations, difficulty in arranging accommodations, and not asking for needed accommodation. Conclusions: Many IBD patients need accommodations at work while symptomatic in order to overcome workplace disability, which can be difficult to arrange. Improved resources are needed to inform employees and employers about the disease, the possibilities for workplace accommodations, and practical strategies to request them.

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Education, Employment, Income, and Marital Status Among Adults Diagnosed With Inflammatory Bowel Diseases During Childhood or Adolescence

Cited by 20 publications

References 26 publications

A Verbal Fluency Task‐Based Brain Activation fMRI Study in Patients with Crohn's Disease in Remission

A Verbal Fluency Task‐Based Brain Activation fMRI Study in Patients with Crohn's Disease in Remission

Long-term implications of structured transition of adolescents with inflammatory bowel disease into adult health care: a retrospective study

Overcoming Workplace Disability in IBD Patients: An Observational Study

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