Editorial: The heart of NAFLD

Chew, Nicholas; Kannan, Shankar; Chong, Bryan; Chin, Yip Han; Muthiah, Mark

doi:10.3389/fmed.2023.1209625

Cited by 6 publications

(1 citation statement)

References 43 publications

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“…Due to the data of numerous studies, an increased level of ADMA in blood plasma was seen in patients with a combination of CHD with hypercholesterolemia, hypertension, diabetes mellitus (DM) type 2 and insulin resistance, hypertriglyceridemia, hyperhomocysteinemia [5,6,7]. Distinct attention is paid to the close relationship between CHD and the pathology of the hepatobiliary system, primarily with non-alcoholic fatty liver disease (NAFLD) [8,9]. In particular, research in recent years has proven that NAFLD acts a considerable role in the formation of risk factors for CVD.…”

Section: клінічна та експериментальна медицина / Clinical and Experim...mentioning

confidence: 99%

Features of the Functional State of the Liver and Indicators of Endothelial Dysfunction in Patients With Coronary Heart Disease Combined With Non-Alcoholic Fatty Liver Disease

Ihnatko,

Derbak,

Chubirko

et al. 2024

VPBM

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Вісник проблем біології і медицини -2024 -Вип. 1 (172) / Bulletin of problems in biology and medicine -2024 -Issue 1 (172) 156 КЛІНІЧНА ТА ЕКСПЕРИМЕНТАЛЬНА МЕДИЦИНА / CLINICAL AND EXPERIMENTAL MEDICINE of Baku. During the seven-year study period (2013)(2014)(2015)(2016)(2017)(2018)(2019)(2020), 559 patients were diagnosed with MS. Of these, 392 (70.1%) patients were female and 167 (29.9%) were male. At the same time, in 390 (69.9%) patients the disease had recurrent (RMS), 109 (19.5%) had progressive (PMS) types of course, and 60 (10.6%) had a clinically isolated syndrome (CIS). CIS was more common in the age group of 20-29 years, RMS in the group of 30-39 years, and PMS was typical in the groups of 40-49 and 50-59 years. The manifestation of the disease in the CIS and RMS groups began at almost the same age (26.0 (24.0-34.0) and 27.0 (22.0-34.0)), with clinical manifestations of damage in one functional system, with a statistically significant difference in age with PRS (34.0 (25.0-41.0)), where the catastrophe was observed in several functional systems. Atrophic changes on MRI of the brain predominated in the group of patients with PMS type of course from the first symptoms of the disease (21.1% of cases), and with subsequent visualizations it tended to increase, reaching 57.4%. In patients treated with a drug that modifies the course of MS -beta interferon 1a, by the end of the year of treatment, EDSS in the CIS and PMS groups remained stable (3.0 (2.0-4.0) and 4.25 (4.0-5.5), respectively), while in the RMS group there was a statistically significant improvement in clinical condition (2.0 (1.0-4.0)).

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