Editorial: Pathophysiology and pharmacological treatments associated with liver failures

Abstract

Editorial on the Research Topic Pathophysiology and pharmacological treatments associated with liver failuresThis editorial summarizes the contributions to the Frontiers Research topic "pathophysiology and pharmacological treatments associated with liver failures" with peer-reviewed articles published in Frontiers in Pharmacology.Liver diseases (LD), which refers to chronic and acute hepatic failures, represent one of the main global health threats on the human life with associated high mortality. Several etiologies have been identified with relevance to the onset of liver diseases and disease progression, including excess alcohol consumption, inflammatory bowel disease, obesity and metabolic disorders; particularly diabetes and insulin-resistance, autoimmune and viral (HBV, HCV) hepatitis, drugs such as acetaminophen overdose and some mycotoxins (eg. aflatoxins) (