Editorial: Lipid metabolism and membrane structure in plant biotic interactions

Goggin, Fiona L.; Shah, Jyoti; Gillaspy, Glenda E.

doi:10.3389/fpls.2022.1096268

Cited by 2 publications

(1 citation statement)

References 25 publications

(32 reference statements)

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“…Moreover, certain amino acids are also precursors of secondary metabolites, such as acetyl coenzyme A, which are formed by the degradation of leucine, isoleucine, lysine and valine, and are important precursor for the synthesis of terpenoids [14,22,[28][29][30][31]. Additionally, many key physiological processes in plants, such as water regulation, cytoskeleton activity, programmed cell death (PCD) activation or root hair growth, are regulated by complex signal transduction networks mediated by lipids [32][33][34][35][36]. Thus, we hypothesized that the accumulation of a large number of primary metabolites is necessary for the rapid development of the young tissues in 1-year-old P. notoginseng taproots, and that these primary metabolites also provides precursors for secondary metabolites production at the later stages of development.…”

Section: Discussionmentioning

confidence: 99%

Integrated metabolome and transcriptome analyses reveal the molecular mechanism underlying dynamic metabolic processes during taproot development of Panax notoginseng

Li,

Zhao,

et al. 2024

BMC Plant Biol

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Background Panax notoginseng (Burk) F. H. Chen is one of the most famous Chinese traditional medicinal plants. The taproot is the main organ producing triterpenoid saponins, and its development is directly linked to the quality and yield of the harvested P. notoginseng. However, the mechanisms underlying the dynamic metabolic changes occurring during taproot development of P. notoginseng are unknown. Results We carried out metabolomic and transcriptomic analyses to investigate metabolites and gene expression during the development of P. notoginseng taproots. The differentially accumulated metabolites included amino acids and derivatives, nucleotides and derivatives, and lipids in 1-year-old taproots, flavonoids and terpenoids in 2- and 3-year-old taproots, and phenolic acids in 3-year-old taproots. The differentially expressed genes (DEGs) are related to phenylpropanoid biosynthesis, metabolic pathway and biosynthesis of secondary metabolites at all three developmental stages. Integrative analysis revealed that the phenylpropanoid biosynthesis pathway was involved in not only the development of but also metabolic changes in P. notoginseng taproots. Moreover, significant accumulation of triterpenoid saponins in 2- and 3-year-old taproots was highly correlated with the up-regulated expression of cytochrome P450s and uridine diphosphate-dependent glycosyltransferases genes. Additionally, a gene encoding RNase-like major storage protein was identified to play a dual role in the development of P. notoginseng taproots and their triterpenoid saponins synthesis. Conclusions These results elucidate the molecular mechanism underlying the accumulation of and change relationship between primary and secondary metabolites in P. notoginseng taproots, and provide a basis for the quality control and genetic improvement of P. notoginseng.

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