Editorial: HIV and NCDs: inevitable interaction in resource limited settings.

Tumwine, James K

doi:10.4314/ahs.v17i4.1

Cited by 6 publications

(9 citation statements)

References 34 publications

(32 reference statements)

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“…Concerning the effect of CAN on QT, several clinical and experimental studies have shown different effects. Ukpabi OJ showed that QTc is significantly more affected by autoimmune neuropathy than other variables in DM patients [9].…”

Section: Introductionmentioning

confidence: 99%

The relationship between QT interval indices with cardiac autonomic neuropathy in diabetic patients: a case control study

Vasheghani

Sarvghadi

Beyranvand

et al. 2020

Diabetol Metab Syndr

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Background Long QT interval (QT) and abnormal QT dispersion (QTd) are associated with sudden death. The relationship between cardiac autonomic neuropathy (CAN) and QT indices in type 2 diabetic patients were investigated. Methods Totally 130 diabetic subjects (mean age 50.87 ± 13.9 years) were included (70 individuals with and 60 individuals without CAN). All participants had sinus cardiac rhythm. The patients who had diseases or take drugs that cause orthostatic hypotension (OH), cardiac arrhythmia and QT prolongation were excluded. After interview and examination, standard and continuous ECG was taken in supine position with deep breathing and standing up position. CAN diagnosis was based on Ewing’s tests. QT, QT corrected (QTc), minimum QT (QT min), maximum QT (QT max) and mean ± SD of QT (QT mean) and QTd were assessed from standard ECG. QTc was calculated by Bazett’s formula from V2 lead. QTc > 440 ms in men and QTc > 460 ms in women and QTd > 80 ms were considered abnormal. Results In patients with CAN, 21.5% were symptomatic. The prevalence of abnormal QTc and QTd was 11.3% and 28.7%, respectively. There was no significant difference between the patients with or without CAN in terms of long QTc and abnormal QTd. However, the mean ± SD of QT max, QT mean and QTd was higher in the patients with CAN (P value < 0.03). The used cut points for QTc and QTd have high specificity (79% for both) and low sensitivity (30% and 37%, respectively). To use QTc and QTd as screening test for CAN in T2DM patients, the cutoff points 380 and 550 ms are suggested, respectively. Conclusion The prevalence of asymptomatic CAN was 3.7 times that of symptomatic CAN. In patients with CAN the QT max, QT mean and QTd were higher than those without CAN. There was no association between CAN and long QTc and abnormal QTd.

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Section: Introductionmentioning

confidence: 99%

The relationship between QT interval indices with cardiac autonomic neuropathy in diabetic patients: a case control study

Vasheghani

Sarvghadi

Beyranvand

et al. 2020

Diabetol Metab Syndr

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“…Infection control at health units is necessary to minimize possible nosocomial infections, such as puerperal and neonatal sepsis, that are major causes of maternal and infant mortality. Poor infection control also carries possible risk of cross transmission of HIV [34][35][36] .…”

Section: Discussionmentioning

confidence: 99%

Capacity assessment for provision of quality sexual reproductive health and HIV-integrated services in Karamoja, Uganda

Marotta¹,

Lochoro²,

Pizzol³

et al. 2020

Afr H. Sci.

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Introduction: Sexual and reproductive health (SRH) and Human Immunodeficiency Virus (HIV) are crucial global health issues. Uganda continues to sustain a huge burden of HIV and AIDS. Methods: A cross-sectional health facility-based assessment was performed in November and December 2016 in Karamoja Region, northern Uganda. All the 126 health facilities (HFs) in Karamoja, including 5 hospitals and 121 Health Centers (HCs), covering 51 sub-counties of the 7 districts were assessed. We assessed the capacity of a) leadership and governance, b) human resource, c) service delivery, d) SRH and HIV service integration and e) users satisfaction and perceptions. Results: 64% of the established health staffing positions were filled leaving an absolute gap of 704 units in terms of human resources. As for service delivery capacity, on 5 domains assessed, the best performing was basic hygiene and safety measures in which 33% HCs scored “excellent”, followed by the presence of basic equipment. The level of integration of SRH/HIV services was 55.56%. Conclusion: HFs in Karamoja have capacity gaps in a number of health system building blocks. Many of these gaps can be addressed through improved planning. To invest in improvements for these services would have a great gain for Uganda. Keywords: Quality Sexual Reproductive Health; HIV-Integrated Services; Karamoja, Uganda.

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“…Long QT is more prevalent in female, Type 1 Diabetes Mellitus (T1DM), long standing DM and patients with chronic complication of DM. 9,16,20 Factors such as race have not yet received especial attention. The prevalence of long-distance QT in blacks, yellows, and Caucasians races was 12% 9 , 17% 21 , and 44% 16 , respectively.…”

Section: Long Qt and Dmmentioning

confidence: 99%

“…Ukpabi OJ showed that QTc is signi cantly more affected by autoimmune neuropathy than other variables in DM patients. 9 Increased QTd is correlated with CAN. High QTd indicates a dysfunction of the autonomic system of heart in patients with DM.…”

Section: Introductionmentioning

confidence: 99%

The Relationship between QT Interval Indices with Cardiac Autonomic Neuropathy in Diabetic Patients- A casecontrol_ study

vasheghani

Sarvghadi

Beyranvand

et al. 2020

Preprint

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Background: Long QT interval (QT) and abnormal QT dispersion (QTd) are associated with sudden death. The relationship between cardiac autonomic neuropathy (CAN) and QT indices in type 2 diabetic patients were investigated. Methods: Totally 130 diabetic subjects (mean age 50.87 ± 13.9 years) were included (70 individuals with and 60 individuals without CAN). All participants had sinus cardiac rhythm. The patients who had diseases or take drugs that cause orthostatic hypotension (OH), cardiac arrhythmia and QT prolongation were excluded. After interview and examination, standard and continuous ECG was taken in supine position with deep breathing and standing up position. CAN diagnosis was based on Ewing’s tests. QT, QT corrected (QTc), minimum QT (QT min), maximum QT (QT max) and mean ± SD of QT (QT mean) and QTd were assessed from standard ECG. QTc was calculated by Bazett’s formula from V2 lead. QTc > 440 msec in men and QTc > 0.46 msec in women and QTd > 80 msec were considered abnormal.Results: In patients with CAN, 21.5% were symptomatic. The prevalence of abnormal QTc and QTd was 11.3% and 28.7%, respectively. There was no significant difference between the patients with or without CAN in terms of long QTc and abnormal QTd. However, the mean ± SD of QT max, QT mean and QTd was higher in the patients with CAN (P value <0.03). The used cut points for QTc and QTd have high specificity (79% for both) and low sensitivity (30% and 37%, respectively). To use QTc and QTd as screening test for CAN in T2DM patients, the cutoff points 380 and 550 msec are suggested, respectively. Conclusion: The prevalence of asymptomatic CAN was 3.7 times that of symptomatic CAN. In patients with CAN the QT max, QT mean and QTd were higher than those without CAN .There was no association between CAN and long QTc and abnormal QTd.

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Editorial: HIV and NCDs: inevitable interaction in resource limited settings.

Cited by 6 publications

References 34 publications

The relationship between QT interval indices with cardiac autonomic neuropathy in diabetic patients: a case control study

The relationship between QT interval indices with cardiac autonomic neuropathy in diabetic patients: a case control study

Capacity assessment for provision of quality sexual reproductive health and HIV-integrated services in Karamoja, Uganda

The Relationship between QT Interval Indices with Cardiac Autonomic Neuropathy in Diabetic Patients- A casecontrol_ study

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