Editorial: Guidelines for the Measurement of Solid–Liquid Solubility Data at Atmospheric Pressure

Abstract

Solubility data have frequently been reported without sufficient attention to experimental detail, including a proper description of apparatus and measurements, the evaluation of uncertainties, and the validation of the experimental protocol. This editorial focuses on solubility measurements of solids in liquids at atmospheric pressure. It provides guidelines that are intended to help researchers to select and validate appropriate experimental techniques, and consequently improve the accuracy of their measured data. It should also assist reviewers in assessing the reliability of solubility data considered for publication in this Journal.

Counterion Condensation, the Gibbs Equation, and Surfactant Binding: An Integrated Description of the Behavior of Polyelectrolytes and Their Mixtures with Surfactants at the Air–Water Interface

“…73,89 Turbidity may, of course, arise without a phase transition and the most reliable alternative is then to measure the phase change "via a discontinuity in a property associated with it". 100 In this case, the ST is just such a property and shows a sharp and easily measured transition 74 with the expected polymer concentration dependence (Figure 14) 74 and in agreement with independent non-ST measurements. 73,89 However, although VC measured the ST, the measurements did not extend to the equivalence point, which is close to where the onset of precipitation would be expected (Figure 10).…”

“…99 In the measurement of low solubility crystallizations, vigorous agitation is considered to be a prerequisite to ensure transformation through metastable intermediates to the final thermodynamic state. 100 The phase diagram of NaPSS-C 16 TAB obtained by Sitar et al, 88 and discussed above, not only used vigorous mixing conditions but also used the other key step in such measurements, which is the structural characterization of the final precipitate. 100 The achievement of surface equilibrium of a sparingly soluble solute, even without the complication of in situ formation, is also challenging and requires special procedures to maintain a saturated monolayer, as illustrated by a series of measurements by Franses et al on the surface behaviour of long chain alkanols.…”

Solid-liquid phase equilibrium of trans-cinnamic acid, p-coumaric acid and ferulic acid in water and organic solvents: Experimental and modelling studies

“…Ji and co-authors [10] employed the gravimetric method for the quantification analysis of the saturated solution, while the UVeVis spectroscopy was preferred in this work. As discussed by K€ onigsberger [54], several parameters, from compound purities to the analytical methods influence the final solubility value. To check the accuracy of the solubility values obtained in this work, the experiments were repeated for p-coumaric acid in alcohols, at both temperatures, but no significant changes were observed.…”

Solubility Temperature Dependence of Bio-Based Levulinic Acid, Furfural, and Hydroxymethylfurfural in Water, Nonpolar, Polar Aprotic and Protic Solvents

“…More specifically, the use of the carbonyl group peak for the determination of concentration has already been described in the literature [34]. To support the validity of the reported data, we describe the procedure in detail as was excellently described and suggested by Königsberger [35].…”