Editorial: Exercise-induced oxidative stress and the role of antioxidants in sport and exercise

Moir, Hannah J.; Maciejczyk, Marcin; Maciejczyk, Mateusz; Aidar, Felipe J.; Arazi, Hamid

doi:10.3389/fspor.2023.1269826

Cited by 4 publications

(3 citation statements)

References 13 publications

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“…It can lead to adverse effects such as muscle pain and physical exhaustion ( Wan et al, 2017 ). Oxidative stress, a physiological response characterized by excessive ROS generation within cells, plays a crucial role in exercise-induced fatigue ( Moir et al, 2023 ). Oxidative stress leads to cellular oxidative damage.…”

Section: Discussionmentioning

confidence: 99%

Impact of Pediococcus pentosaceus YF01 on the exercise capacity of mice through the regulation of oxidative stress and alteration of gut microbiota

Yang,

Wang,

Yang

2024

Front. Microbiol.

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Using treadmill training, this study replicated human exercise conditions and triggered exercise-induced fatigue in mice to examine the potential of Pediococcus pentosaceus YF01 in delaying this fatigue by regulating oxidative stress and its impact on the exercise capacity and gut microbiota of mice. The exercise capacity of mice was tested by conducting exhaustion tests, determining histopathological changes in mouse tissues, detecting the levels of serum biochemical markers, and evaluating the mRNA expression levels of relevant genes. YF01 prolonged the exhaustion time of mice, increased the serum levels of oxidative stress-related markers T-AOC, CAT, and GSH, as well as GLU and LA levels in the mice. YF01 decreased the levels of hepatic-related markers AST and ALT, as well as exercise-related markers LDH, BUN, UA, and CRE in the mice. YF01 upregulated the mRNA expression of MyHc I, SIRT1, and PGC in muscle tissues, as well as SOD1, SOD2, and CAT in both liver and muscle tissues. YF01 also downregulated the mRNA expression of MyHc IIa, MyHc IIb, and MyHc IIx in muscle tissues. Furthermore, YF01 increased the abundance of beneficial bacteria such as Lactobacillus and Lachnospiraceae in the gut microbiota of mice. In conclusion, P. pentosaceus YF01 may affect the exercise capacity of mice by modulating oxidative stress levels, thereby offering novel ideas for developing of sports science and human health.

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Section: Discussionmentioning

confidence: 99%

Impact of Pediococcus pentosaceus YF01 on the exercise capacity of mice through the regulation of oxidative stress and alteration of gut microbiota

Yang,

Wang,

Yang

2024

Front. Microbiol.

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“…Oxidative stress, characterized by an imbalance between reactive oxygen species (ROS) and nitrogen species (RNS) with antioxidant defenses, can directly damage cellular components and exacerbate tissue injury. Meanwhile, inflammation acts as a double-edged sword, initiating the healing cascade but also contributing to secondary tissue damage if left unchecked [ 61 , 79 ]. Supplementation with approximately 4 g/day of ω-PUFA, which is abundant in EPA and DHA, over 8 weeks demonstrated efficacy in mitigating several parameters associated with oxidative stress and inflammation resulting from acute intense physical exertion [ 80 ].…”

Section: ω-3 Index and Sports Injury Preventionmentioning

confidence: 99%

Omega-3 Index as a Sport Biomarker: Implications for Cardiovascular Health, Injury Prevention, and Athletic Performance

Medoro,

Buonsenso,

Centorbi

et al. 2024

JFMK

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The composition of polyunsaturated fatty acids (PUFA) in the cell membrane plays a crucial role in cell signaling and function. Physical activity can induce shifts in PUFA metabolism, potentially altering their membrane composition. Given the multifaceted regulatory and structural roles of PUFA, training-related fluctuations in PUFA concentrations may impact health and athletic performance in both elite and non-elite athletes, highlighting the critical role of these fatty acids’ nutritional intake. The ω-3 index (O3I), a biomarker reflecting the proportion of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in red blood cell membranes, is considered a marker of cardiovascular risk, gaining increasing interest in sports medicine. Dietary interventions aimed at maintaining an optimal O3I may offer several benefits for elite and non-elite athletes, including cardiovascular health performance optimization, recovery, and injury prevention. Here, we discuss emerging evidence on the application of O3I in sports and physical exercise, highlighting its promising role as a biomarker in a wide range of sports practices.

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“…It can lead to adverse effects such as muscle pain and physical exhaustion (Wan et al, 2017). Oxidative stress, a physiological response characterized by excessive ROS generation within cells, plays a crucial role in exerciseinduced fatigue (Moir et al, 2023). Oxidative stress leads to cellular oxidative damage.…”

Section: Discussionmentioning

confidence: 99%

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Editorial: Exercise-induced oxidative stress and the role of antioxidants in sport and exercise

Cited by 4 publications

References 13 publications

Impact of Pediococcus pentosaceus YF01 on the exercise capacity of mice through the regulation of oxidative stress and alteration of gut microbiota

Impact of Pediococcus pentosaceus YF01 on the exercise capacity of mice through the regulation of oxidative stress and alteration of gut microbiota

Omega-3 Index as a Sport Biomarker: Implications for Cardiovascular Health, Injury Prevention, and Athletic Performance

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