Editorial comment Re: Elliott CS, Comiter CV. The effect of angiotensin inhibition on urinary incontinence: Data from the National Health and Nutrition Examination Survey (2001–2008). Neurourol urodyn 2014; 33:1178–81

Denys, Marie‐Astrid; Goessaert, An-Sofie; Everaert, Karel

doi:10.1002/nau.22478

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…11 Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers reduce both detrusor overactivity and urethral sphincter tone, resulting in reduced urge incontinence and increased stress urinary incontinence. 12 On the other hand, antidepressants cause urinary retention that leads to overflow incontinence. Benzodiazepines result in relaxation of striated muscles due to effects on γ-aminobutyric acid receptors resulting in functional incontinence.…”

Section: Introductionmentioning

confidence: 99%

Antiepileptic Drugs–Induced Enuresis in Children: An Overview

Sathyan

Scaria

Arunachalam

et al. 2020

Journal of Pharmacy Technology

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Objective: To evaluate enuresis-induced antiepileptic drugs in children. Data Sources: A PubMed search (1917 to July 2020) was performed using the following keywords and associated medical subject headings: antiepileptic drugs, enuresis, pediatric population, drug-induced enuresis, and epilepsy. Study Selection and Data Extraction: The search was conducted to find the role of antiepileptic drugs–induced enuresis in children in studies published in English. Data Synthesis: Enuresis or bedwetting is an underreported adverse drug reaction of antiepileptic drugs. Owing to that fact, it is a condition that is outgrown with age and also could cause embarrassment. As antiepileptic drugs sometimes need to be taken for a long duration until epilepsy relapses, the occurrence of enuresis in this situation can be troublesome for both the child and the caretaker. Even though enuresis is proposed to have a significant effect on the child’s psychology, it is still considered to be a condition that is outgrown with age. This article includes a review of antiepileptic drugs reported to have caused enuresis in children. Conclusions: If a child develops enuresis as an adverse drug reaction, this adds further challenges to their life. A better understanding of this potential adverse effect may help prevent unwanted stress. Though the exact mechanisms are not known, the hypothesis generated is from the occurred cases, most of which relapsed when the drug was withdrawn. Considering the gravity of epilepsy in children, more detailed studies need to be conducted on this adverse effect to ensure a safe and effective treatment in children.

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Section: Introductionmentioning

confidence: 99%

Antiepileptic Drugs–Induced Enuresis in Children: An Overview

Sathyan

Scaria

Arunachalam

et al. 2020

Journal of Pharmacy Technology

View full text Add to dashboard Cite

show abstract

Polypharmacy in Older People with Heart Failure: Roles of the Geriatrician and Pharmacist

et al. 2022

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Heart failure (HF) is a common health condition that typically affects older adults. Many people with HF are cared for on an inpatient basis, by non-cardiologists, such as acute medical physicians, geriatricians and other physicians. Treatment options for HF are ever increasing, and adherence to guidelines for prognostic therapy contributes to polypharmacy, which is very familiar to clinicians who care for older people. This article explores the recent trials in both HF with reduced ejection fraction and HF with preserved ejection fraction and the limitations of international guidance in their management with respect to older people. In addition, this article discusses the challenge of managing polypharmacy in those with advanced age, and the importance of involving a geriatrician and pharmacist in the HF multidisciplinary team to provide a holistic and person-centred approach to optimisation of HF therapies.

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Editorial comment Re: Elliott CS, Comiter CV. The effect of angiotensin inhibition on urinary incontinence: Data from the National Health and Nutrition Examination Survey (2001–2008). Neurourol urodyn 2014; 33:1178–81

Cited by 2 publications

References 9 publications

Antiepileptic Drugs–Induced Enuresis in Children: An Overview

Antiepileptic Drugs–Induced Enuresis in Children: An Overview

Polypharmacy in Older People with Heart Failure: Roles of the Geriatrician and Pharmacist

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