Editorial: clinical outcomes in lean NAFLD – the devil is in the details. Authors' reply

Abstract

We read with great interest the editorial by Tan et al 1 on our recent study on clinical outcomes in patients with lean non-alcoholic fatty liver disease (NAFLD), where we found that lean patients with NAFLD experienced higher mortality than patients with overweight or obesity, despite lower prevalence of baseline metabolic disease and lower incidence of cirrhosis and diabetes.We would like to clarify how our cohort was generated and the rationale for this approach. 2 We identified patients with hepatic steatosis based on simple natural language processing algorithms applied to imaging, biopsy, and vibration-controlled transient elastography re-Medicine