Abstract:A substantial body of evidence supports the safety of conservative
endoscopic polypectomy for discrete, adenomatous-appearing, colonic polyps in
patients with ulcerative colitis. Much less is known about the clinicopathologic
factors of low-grade dysplastic lesions at risk for subsequent high-grade
dysplasia or colorectal cancer. In this issue of the American Journal of
Gastroenterology, Choi and colleagues examine the outcome of
patients with low-grade dysplasia participating in a surveillance cohort at St.
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