Editorial: Bioinformatics of Genome Regulation, Volume II

Orlov, Yuriy L.; Anashkina, Anastasia A.; Tatarinova, Tatiana V.; Baranova, Ancha

doi:10.3389/fgene.2021.795257

Cited by 7 publications

(15 citation statements)

References 20 publications

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“…Accordingly, we organized this Research Topic to collect the papers focused on studying ancestry specific variation in various human diseases. This Topic complements recent Research Topic Bioinformatics of Genome Regulation in Frontiers in Genetics considered more genetic background rather than molecular mechanisms of the human diseases (Orlov et al, 2021a).…”

Section: Editorial For the Research Topic Association Between Individ...mentioning

confidence: 76%

“…The BGRS\SB (Bioinformatics of Genome Regulation and Structure\Systems Biology) multi-conference (https://bgrssb. icgbio.ru/2020) has been organized in Novosibirsk, Russia in 2020 and was associated with the Research Topic on gene expression regulation in Frontiers in Genetics (see also https:// www.frontiersin.org/research-topics/8383/bioinformatics-ofgenome-regulation-and-systems-biology) (Orlov et al, 2016a, Orlov et al, 2016b, Tatarinova et al, 2019Orlov et al, 2021a).…”

Section: Editorial For the Research Topic Association Between Individ...mentioning

confidence: 99%

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Editorial: Association Between Individuals’ Genomic Ancestry and Variation in Disease Susceptibility

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Section: Editorial For the Research Topic Association Between Individ...mentioning

confidence: 76%

Section: Editorial For the Research Topic Association Between Individ...mentioning

confidence: 99%

Editorial: Association Between Individuals’ Genomic Ancestry and Variation in Disease Susceptibility

et al. 2022

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“…Thus, we have organized this Research Topic to collect the papers focused on the frontiers of chronic disease markers. This Topic complements recent Research Topics "Bioinformatics of Genome Regulation" (Orlov et al, 2021a) and "Association between Individuals' Genomic Ancestry and Variation in Disease Susceptibility" in Frontiers in Genetics (Das et al, 2022). The later journal issue collected papers focused on genetic background and ancestry rather than on molecular mechanisms of the human diseases (Das et al, 2022).…”

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confidence: 91%

Editorial: High-Throughput Sequencing-Based Investigation of Chronic Disease Markers and Mechanisms

et al. 2022

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Editorial on the Research Topic High-throughput sequencing-based investigation of chronic disease markers and mechanismsThis "High-throughput sequencing-based investigation of chronic disease markers and mechanisms" issue focuses on the genomics studies on cancer and chronic diseases. With the recent development of sequencing technology and the rapid reduction of sequencing costs, high-throughput sequencing (including second and third-generation sequencing) is revolutionizing basic life science research and clinical research. High-throughput sequencing often produces millions of sequencing reads at a time, and the alignment or assembly of these reads allows determination of various mutations at the genomic level, accurate gene expression quantification at the transcriptomic level, and identification of histone or DNA modification at the epigenomic level. The resulting accumulation of enormous multi-omics information has opened up a new era of finding effective disease markers and studying their roles in disease occurrence and development (Anashkina et al., 2021).Using high-throughput sequencing, various markers of chronic diseases have been developed at all omics levels, which have been used for diagnosis and classification of diseases, prediction of treatment effects, and prevention of diseases (Voronova et al., 2020;Glukhov et al., 2021). The chronic diseases include cancer, heart disease, diabetes, arthritis. The quickly and massively acquired multi-omics data, together with newly developed algorithms, provide excellent opportunities for the identification of more reliable biomarkers. This Research Topic aimed at 1) developing new chronic disease markers at four levels (i.e., genome, epigenome, transcriptome, and translatome) with the help of highthroughput sequencing, and 2) delineating potential marker-related mechanisms for chronic disease occurrence or development. More specifically, this Research Topic contains contributions including: 1) Identification of novel biomarkers and prediction signatures for chronic disease detection or prognosis prediction using high-throughput sequencing; 2) Analysis the possible pathological causes of markers as well as the potential roles they play in disease initiation and development; 3) Applications of new high-throughput sequencing techniques facilitating the development of more effective biomarkers of chronic disease;

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“…This Special Issue continues the collection of papers published in MDPI IJMS “Bioinformatics of Gene Regulations and Structure” ( , accessed on 14 June 2022) [ 3 ] and related journal issues initiated after the series of bioinformatics conferences that were held in Russia—BGRS ( , accessed on 14 June 2022) and Plantgen-21 (14–18 June 2021, Novosibirsk, Russia, , accessed on 14 June 2022) [ 1 , 2 , 6 ]. Some of the studies presented here were reported at the BGRS (Bioinformatics of Genome Regulation and Structure/Systems Biology) traditional biannual computational biology meeting in Novosibirsk, Russia [ 7 , 8 ].…”

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confidence: 99%

“…To note history of the series of post-conference journal Special Issues we refer to Bioinformatics of Genome Regulation and Structure (BGRS) conference series [ 1 , 2 , 6 , 10 , 11 ] and related Schools on Systems Biology and Bioinformatics (SBB) held in Novosibirsk, Russia [ 7 , 9 , 18 ], later completed by other international conferences on genetics such as Belyaev Conference—2017 [ 19 ]. Here we collected works on the topics of gene expression regulation in plants; plant genomics and bioinformatics; plant stress response; miRNA and molecular mechanisms studies in plants; plant systems biology and digital phenotyping.…”

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confidence: 99%