Abstract:As noted above, the first attempt to treat animals was tried by d'Herelle after he first identified bacteriophage but before their identity as viruses was known. W.W.C. Topley, an early phage researcher noted in his 1925 public lecture on "the bacteriophage principle" that "it is a conceivable hypothesis that the administration of a lytic filtrate, Frontiers in Microbiology frontiersin.org
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