Edge Vascular Response After Resorption of the Everolimus-Eluting Bioresorbable Vascular Scaffold　– A 5-Year Serial Optical Coherence Tomography Study –

Early strut protrusion and late neointima thickness in the Absorb bioresorbable scaffold: a serial wall shear stress analysis up to five years

“…Step-up and step-down in luminal dimensions at the inlet and outlet of the scaffold generate macro-changes in WSS and modulate neointimal proliferation that will ultimately homogenise luminal dimensions in the proximal, distal and scaffolded segments 20 . The morphological improvement in transitional zones was completed at one year 21 .…”

Coronary Shear Stress after Implantation of Bioresorbable Scaffolds – a Modern Interdisciplinary Concept at the Border between Interventional Cardiology and Cardiac Imaging

“…Normal shear stress has to be the main criteria for an optimal implantation; this means optimal stent apposition, no protrusion of struts in the vascular lumen that can disturb the blood flow, no significant difference between the diameter of the proximal and distal end of a stented segment (in other words the perfect incorporation of stents in the vascular wall), no asymmetry of the blood vessel, and a bioresorbable scaffold/artery ratio between 1 and 1.1. 84 In fact, only intravascular imaging techniques can accurately evaluate the criteria mentioned above for optimal implantation. Only OCT with a resolution of 20 microns can examine the blood vessel and the interaction with the bioresorbable stent for the required precision.…”

“…Only OCT with a resolution of 20 microns can examine the blood vessel and the interaction with the bioresorbable stent for the required precision. 84,85 The possibility of identifying a pathologic alteration of shear stress using computational simulations based on fluid dynamics in the coronary regions, after the implantation of a stent, as well as achieving dynamic simulations, could open up new horizons for percutaneous transluminal coronary revascularization.…”

Impact of Implantation Technique and Plaque Morphology on Strut Embedment and Scaffold Expansion of Polylactide Bioresorbable Scaffold – Insights From ABSORB Japan Trial –

“…In a previous publication by Sadamatsu et al, lesion preparation with a CB balloon achieved equivalent stent expansion to a NC balloon, even with lower pressure and a smaller diameter mean balloon-artery ratio at postdilatation was 1.16±0.13, which resulted in excellent 5-year results without any unfavorable edge vascular responses. 25 In other words, a 3.48-mm postdilatation balloon could be used for a 3.0-mm RVD, at least for simple lesions. From that point of view, a 0.25-mm larger postdilatation using a NC balloon might be a practical guideline.…”