Edema bilateral del nervio óptico por leucemia linfocítica crónica

Sáenz-Francés, F.; Calvo-González, C; Reche-Frutos, J; Donate-López, J.; Huelga-Zapico, E; Garcı́a-Sánchez, José Elı́as; García‐Feijoó, Julián

doi:10.4321/s0365-66912007000500010

Cited by 3 publications

(1 citation statement)

References 5 publications

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“…Several reports exist concerning the relationship between papilledema and acute myeloid leukemia,[526] acute lymphoblastic leukemia,[7911174752] chronic myelogenous leukemia,[14] and chronic lymphocytic leukemia. [39] In a study of 82 children with acute leukemia, Reddy et al . [37] found that only 3 children complained of eye symptoms.…”

Section: Discussionmentioning

confidence: 99%

Unusual causes of papilledema: Two illustrative cases

Nguyen

Haider²,

Ackerman³

2013

Surg Neurol Int

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Background:Neurosurgeons are frequently among the first physicians asked to evaluate patients with papilledema, and the patient is often referred with the implication that they may require shunting. After an initial evaluation to exclude potential neurosurgical emergencies, the physician should carefully consider various etiologies of papilledema to prevent unnecessary neurosurgical operations.Case Description:The authors report two illustrative cases of unusual causes of papilledema: Anemia and leukemic infiltration of the central nervous system. In each case, a complete blood count provided clues for the diagnosis. A review of the literature is also included.Conclusions:Both patients responded to medical management/treatment of the underlying disease and did not require neurosurgical operative intervention. Papilledema may be caused by other etiologies besides increased intracranial pressure. The authors present two unusual cases leading to papilledema and provide an outline for the workup of these conditions.

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Section: Discussionmentioning

confidence: 99%

Unusual causes of papilledema: Two illustrative cases

Nguyen

Haider²,

Ackerman³

2013

Surg Neurol Int

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CLL: Common Leukemia; Uncommon Presentations

Lad

Malhotra

Varma

et al. 2014

Indian J Hematol Blood Transfus

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We report here a series of ten patients with uncommon presentations and associations of chronic lymphocytic leukemia (CLL) not reported hitherto or occasionally reported in literature. The first two cases describe unusual causes of abdominal distension in CLL and unusual sites infiltration by CLL. The next two cases illustrate occurrence of CLL in association with other hematological malignancies. Cases five and six describe unusual infections and their impact on CLL. Cases seven and eight depict associations of rare non-hematological autoimmune conditions with CLL. The last two cases describe transformation at unusual sites. This series of ten cases illustrates how a common leukemia like CLL can present in different forms and how despite so much progress in understanding of this leukemia so little is known of such presentations.

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Leptomeningeal involvement in B-cell chronic lymphocytic leukemia: a case report and review of the literature

et al. 2014

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BackgroundCentral nervous system involvement is considered a rare complication of chronic lymphocytic leukemia, and so there is the risk of being overlooked.Case presentationWe report a case of central nervous system involvement in a 75-year-old mulatto woman with chronic lymphocytic leukemia after 5 years of follow-up and a literature review on the subject. The clinical course, treatment and outcome are described. A systematic, meticulous and comprehensive analysis of existing publications regarding chronic lymphocytic leukemia with central nervous system involvement was performed.ConclusionWe concluded that central nervous system involvement of chronic lymphocytic leukemia is probably not associated with any evident risk factors. Diagnostic approach differs by institutions but often includes imaging, morphology and flow cytometry. Resolution of central nervous system symptoms can usually be accomplished with intrathecal chemotherapy or irradiation followed by systemic treatment. The recognition of this entity by clinicians could lead to early detection and treatment, resulting in better outcomes in this rare complication.

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Edema bilateral del nervio óptico por leucemia linfocítica crónica

Cited by 3 publications

References 5 publications

Unusual causes of papilledema: Two illustrative cases

Unusual causes of papilledema: Two illustrative cases

CLL: Common Leukemia; Uncommon Presentations

Leptomeningeal involvement in B-cell chronic lymphocytic leukemia: a case report and review of the literature

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