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Abstract

Recently, heterocyclic compounds analogues and their derivatives have attracted strong interest in medicinal chemistry due to their biological and pharmacological properties. The small and simple benzothiazole nucleus possesses numerous biological properties like -antitumor, antimicrobial, anti-inflammatory, anticonvulsant, and antidiabetic activities. These activities are also possessed by its substituted derivatives as well. The present review focuses on some commonly used easy procedures to synthesize the benzothiazole moiety and its derivatives, which comprise of different biological activities.

In vitro release study of 2-aminobenzothiazole from microspheres as drug carriers

“…Antimicrobial drugs have long been used for drug therapy in the field of infectious disease. Many substituted benzothiazole are at the forefront in the 532 MERDOUD et al search for new antimicrobial agents, 1,2 given the isosteric relationship between the SH and NH 2 groups. 3 Recently, a research group was interested in the in vitro antifungal activities of synthesized 2-amino-benzothiazole derivatives and showed their novel structure leads to potent antimicrobial activity.…”