ED visits by males with hemophilia

Nuss, Rachelle; Hoffman, Richard E.; Hammond, Lucinda

doi:10.1053/ajem.2002.30098

Cited by 11 publications

(14 citation statements)

References 12 publications

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“…Disease severity in patients with hemophilia determined on the basis of plasma factor activity level as severe in patients with factor activity (<1%), moderate (1-5%), and mild (6-30%) [15]. In patients with rare bleeding disorders, we considered only severe and not severe type of disease based on plasma factor activity level (<1%) and (>1%), respectively.…”

Section: Methodsmentioning

confidence: 99%

Spectrum of inherited bleeding disorders in southern Iran, before and after the establishment of comprehensive coagulation laboratory

Karimi

Haghpanah

Amirhakimi

et al. 2009

Blood Coagulation &Amp; Fibrinolysis

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The objective of the present study was to determine the pattern of inherited bleeding disorders in southern Iran and evaluate the effect of a comprehensive coagulation laboratory and related efforts. A total of 545 patients with inherited bleeding disorders were evaluated during 1992-2007 by a cross-sectional study. Data were collected by a data-gathering form. Statistical analysis was done using Statistical Package for the Social Sciences version 15. A P value less than 0.05 was considered statistically significant. Overall 411 patients had common bleeding disorders including 326 hemophilia A, 46 hemophilia B, and 39 von Willebrand disease. Seventy-nine patients had rare coagulation disorders including deficiency of factor VII (n = 26), factor X (n = 18), factor XIII (n = 9), factor I (n = 9), factor XI (n = 7), factor V (n = 4), combined factor VIII and factor V (n = 4), and combined factor X and factor VII (n = 2). Fifty-five patients had platelet disorders including 23 with Glanzmann's thrombasthenia, 15 with Bernard-Soulier syndrome, and 17 with other platelet disorders, most of which (45) were diagnosed after the establishment of the comprehensive coagulation laboratory. Annual mean number of new diagnosed patients with common and rare bleeding disorders increased from 29 +/- 4 to 38 +/- 17. The ratio of the patients diagnosed with rare bleeding disorders to common bleeding disorders significantly increased after the establishment of the comprehensive diagnosis laboratory (P < 0.001).It seems that implementation of collaborative projects by the Shiraz Hemophilia Society and the establishment of the comprehensive coagulation laboratory and treatment centers have been successful in increasing diagnosis of the inherited bleeding disorders and consequently better management of the patients.

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Section: Methodsmentioning

confidence: 99%

Spectrum of inherited bleeding disorders in southern Iran, before and after the establishment of comprehensive coagulation laboratory

Karimi

Haghpanah

Amirhakimi

et al. 2009

Blood Coagulation &Amp; Fibrinolysis

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“…Haemophilia is one of the most common inherited bleeding disorders in the ED. 3,4,11,15 Bleeding may occur anywhere in patients with haemophilia but the most dangerous site of bleeding is the central nervous system, because of its high morbidity and mortality. 11,16 The morbidities include seizures, psychomotor and statomotor impairment and a decreased quality of life.…”

Section: Discussionmentioning

confidence: 99%

“…Usual clinical features include recurrent deep tissue and joint bleeding that may lead to long‐term disability. Intracranial haemorrhage (ICH) is the most dangerous event in individuals with haemophilia, spontaneously or after trauma, and the prompt administration of factor is critical in cases of potential ICH …”

Section: Introductionmentioning

confidence: 99%

Head trauma in the haemophilic child and management in a paediatric emergency department: Descriptive study

et al. 2018

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“…In these situations, it is critical to make an accurate and early diagnosis in the ED settings. Single centre or state experience of ED utilization by haemophilia patients has been reported . To the best of our knowledge, this is the first study of ED utilization by haemophilia patients from a national ED database.…”

Section: Discussionmentioning

confidence: 99%

“…According to our study, ‘injury and poisoning’ was the second most common category reported among haemophilia patients during ED visits. Three other paediatric studies published had injuries as the most common category . The most common category of complaints reported in our whole study population was cardiovascular.…”

Section: Discussionmentioning

confidence: 99%