Eczematous Contact-Sensitivity to Gold

Contact allergy to gold in dental patients

“…Ten patients had oral lesions related, at least in part, to gold dental restorations ( Table 1). Replacement of these was performed in six patients (nos 4,7,8,18,30,31). No resolution was seen, after a follow-up of 6-12 months, in patients 4, 7, 8 and 18.…”

Screening for Gold Sensitization in Consecutive Eczema Patients: Prevalence, Relevance, and Sources of Exposure

“…[2][3][4][5] However, gold and its salts were still considered to be rare sensitizers until the last decades of the 20th century despite results from a human maximization test, which pointed to a high sensitizing potential of gold chloride. 1,[6][7][8] A turning point came in the 1990s, after patch test screening with gold sodium thiosulfate (GST) suggested gold to be a frequent sensitizer, and it rose to stardom in 2010 when it was appointed Allergen of the Year. 9,10 The inclusion of GST in the TRUE Test ready-to-use patch test system in 2015 means that routine screening for gold allergy may become more common than previously.…”

Gold Contact Allergy: Clues and Controversies

“…There have been numerous case reports regarding localized contact dermatitis to gold (Supplementary Table 2, http://links.lww.com/DER/A3), particularly involving the eyelids, ears, hands, and neck. 21,36,45,53–63 This may take the form of a chronic papular eruption. 64 Airborne dermatitis has also been reported, particularly involving the eyelids and neck.…”

“…108 In addition, gold trichloride has been reported to cause dermatitis in photography. 55 Occupational dermatitis often presents on exposed acral sites. 109 Sperber et al 4 shared a case of severe hand dermatitis in a jewelry saleswoman who had a positive patch test reaction to gold but not to nickel.…”