Abstract:There is geographical variation in the prevalence of eczema in adults both within and between countries. Although the disease is associated with IgE sensitization, in this study it was not related to mattress mite or cat allergen levels.
“…We have found using data from our work that the lifetime clinician{recorded prevalence peaks in younger children mirrored results from a birth cohort, 13 and the prevalence in our older adults was similar to that found in survey data. 7 Although little data on the trend of eczema prevalence exist prior to World War II (1939)(1940)(1941)(1942)(1943)(1944)(1945), the prevalence of eczema increased substantially in the latter half of the 20th century, with eczema in school{aged children being found to increase between the late 1940s and 2000. [14][15][16] In contrast to our results, survey studies (see Box 2 Trends in the epidemiology and prescribing of medication for eczema in England for questions used in surveys) from the period immediately prior (1995-1996 to 2000-2001) 17 and intersecting our study period (1995-1996 to 2002-2003) 6 found only a moderate increase in eczema in children (2-15 years), a decrease in older children (13-14 years) and no increase in adults (aged >15 years) over time.…”
Section: Main Strengths and Limitations Of This Workmentioning
confidence: 99%
“…Another strength of this study was the use of contemporaneous clinician recording of a diagnosis of eczema as opposed to patient self{reporting of historical diagnoses or symptoms. 6,7 There are a number of limitations related to the use of large routinely collected data from primary care, including the dependence on clinician{ recorded diagnosis of eczema and possible improvements in recording over the study time period. The relatively short time window over which trends were studied is another limitation, but this does also have the advantage of confining analysis to a period during which there were no changes in disease definition or classification.…”
Section: Main Strengths and Limitations Of This Workmentioning
confidence: 99%
“…5 Studying primary care databases provides a picture of overall national trends -something that is not possible with large scale surveys such as ISAAC, which has studied only children, 6 and the ECRHS, which has surveyed only adults. 7 Large primary care data{sets such as QRESEARCH, recording information at the point at which the majority of patients with eczema are likely to be managed, do however offer an important opportunity to study changing patterns of disease. Building on previous work, [8][9][10] we sought to describe recent trends in the primary care diagnosis, prescribing and consulting behaviours of patients with eczema in England.…”
SummaryBackground The prevalence of eczema, particularly in younger children, increased substantially over the second half of the 20th century. Analysis of primary healthcare data-sets offers the possibility to advance understanding about the changing epidemiology of eczema.
“…We have found using data from our work that the lifetime clinician{recorded prevalence peaks in younger children mirrored results from a birth cohort, 13 and the prevalence in our older adults was similar to that found in survey data. 7 Although little data on the trend of eczema prevalence exist prior to World War II (1939)(1940)(1941)(1942)(1943)(1944)(1945), the prevalence of eczema increased substantially in the latter half of the 20th century, with eczema in school{aged children being found to increase between the late 1940s and 2000. [14][15][16] In contrast to our results, survey studies (see Box 2 Trends in the epidemiology and prescribing of medication for eczema in England for questions used in surveys) from the period immediately prior (1995-1996 to 2000-2001) 17 and intersecting our study period (1995-1996 to 2002-2003) 6 found only a moderate increase in eczema in children (2-15 years), a decrease in older children (13-14 years) and no increase in adults (aged >15 years) over time.…”
Section: Main Strengths and Limitations Of This Workmentioning
confidence: 99%
“…Another strength of this study was the use of contemporaneous clinician recording of a diagnosis of eczema as opposed to patient self{reporting of historical diagnoses or symptoms. 6,7 There are a number of limitations related to the use of large routinely collected data from primary care, including the dependence on clinician{ recorded diagnosis of eczema and possible improvements in recording over the study time period. The relatively short time window over which trends were studied is another limitation, but this does also have the advantage of confining analysis to a period during which there were no changes in disease definition or classification.…”
Section: Main Strengths and Limitations Of This Workmentioning
confidence: 99%
“…5 Studying primary care databases provides a picture of overall national trends -something that is not possible with large scale surveys such as ISAAC, which has studied only children, 6 and the ECRHS, which has surveyed only adults. 7 Large primary care data{sets such as QRESEARCH, recording information at the point at which the majority of patients with eczema are likely to be managed, do however offer an important opportunity to study changing patterns of disease. Building on previous work, [8][9][10] we sought to describe recent trends in the primary care diagnosis, prescribing and consulting behaviours of patients with eczema in England.…”
SummaryBackground The prevalence of eczema, particularly in younger children, increased substantially over the second half of the 20th century. Analysis of primary healthcare data-sets offers the possibility to advance understanding about the changing epidemiology of eczema.
“…Studies have suggested the following prevalence: psoriasis 1-8% [2], hidradenitis suppurativa (HS) 0.33-4% [3,4], adult atopic eczema (AE) 0.3-6.2% [5], pimples 3.5% and hand rash 3.3% [6]. Hospital-based studies indicate that skin diseases reduce patients' quality of life (QoL), but the morbidity of these large groups of patients found in the general population is poorly described.…”
Background: Impaired dermatological health-related quality of life (HRQoL) has been observed in hospital-based studies, but little is known on a population-based level. Objective: To investigate self-reported dermatological HRQoL in the general population. Methods: Hidradenitis suppurativa, psoriasis, pimples, hand rash or atopic eczema were identified using questionnaires in a 15,177 person population sample. A nested case-control study of 180 cases and 259 controls was made using the Dermatology Life Quality Index (DLQI), Skindex-29 and EQ-5D. Results: Cases had higher scores in DLQI and Skindex-29 and a lower score in EQ-5D, suggesting lower HRQoL. Adjusting for age and sex, the differences in Skindex-29 and DLQI were significant (p < 0.001). Conclusions: Persons with self-reported skin morbidity had lower HRQoL than the general population. The impairment is not as significant as in studies of hospital-based cases, but considering the high prevalence of skin diseases it may still represent a significant burden of disease on society in aggregate.
“…FA caused by fruits, vegetables, tree nuts, peanuts and seafood seem to be most prevalent in adults [9,10,21] . Sensitization may occur directly to food allergens or indirectly through cross-reactivity with aeroallergens.…”
As populations become older all over the world, allergic reactions in elderly persons will be encountered more often in the future. Up to now, there has been much more literature on allergy prevalence in childhood than on allergy diseases in adults. As a challenge to epidemiology, allergic disorders in elderly persons may be masked by various symptoms corresponding with a general age-induced decline of physiological functions, including vitamin D deficiency and gastric pH increase. How much structural and functional changes (e.g. low calcitriol level) or effects caused by drugs (e.g. acid-suppression medications) in addition to immunological alterations encountered at old age are responsible for this development is a matter of debate. In the years ahead, the problem of allergy in adulthood and especially in the elderly will become more pronounced.
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