Ectopic presacral choroid plexus cyst in a neonate

Gross, Eitan; Koplewitz, Benjamin Z.; Arbell, Dan; Fellig, Jakob; Udassin, Raphael

doi:10.1016/j.jpedsurg.2009.01.015

Cited by 3 publications

(3 citation statements)

References 6 publications

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“…27–29 An ectopic choroid plexus presacral cyst and two cases of intramedullary ectopic normal choroid plexus have also been described. 30–32 Contrary to what might be expected, ectopic sites seem to be more common in adults than in children. 33 This was interesting given the cat was 10 years old, but futher conclusions could not be made as there are no reports of this tumour type in cats.…”

Section: Discussionmentioning

confidence: 62%

“…28,29 Surgical treatment of spinal cord or sacral ectopic choroid plexus or ectopic CPT in humans is associated with neurological improvement and no reoccurrence within a follow-up period of 3 months to 3 years. [28][29][30][31][32] No further chemotherapy or radiotherapy treatment was provided in the above-reported cases. A poor prognosis was associated with ectopic choroid plexus carcinoma with metastasis.…”

Section: Discussionmentioning

confidence: 99%

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Spinal ectopic choroid plexus papilloma in a cat

Tabanez¹,

Beck²,

Driver

et al. 2021

Journal of Feline Medicine and Surgery Open Reports

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Case summary A 10-year-old male neutered Russian Blue cat was presented with a 2-month history of progressive non-ambulatory paraparesis. Spinal MRI revealed a well-demarcated, compressive intradural extramedullary mass at the level of T1 vertebra. The mass had subtle hyperintensity on T2-weighted images, was isointense on T1-weighted images and had diffuse, marked enhancement following gadolinium administration. Neuroaxis MRI, including limited brain sequences, excluded other visible lesions. Thoracic and abdominal radiographs were unremarkable. The mass was resected via a dorsal C7–T2 laminectomy and durotomy. Histopathology revealed a neoplasm composed of columnar-to-polygonal cells forming bilayered palisading patterns with a few apical cilia. Three mitoses were noted in 10 high-power fields. This was consistent with an epithelial neoplasm and initially a metastatic adenocarcinoma was considered most likely. Full-body CT with contrast and including the brain found rhinitis but did not identify any additional neoplastic foci. Biopsies of the nasal cavity and fine-needle aspiration of the spleen and liver were unremarkable. On immunohistochemical evaluation, pan-cytokeratin and E-cadherin immunolabelling was observed; however, synaptophysin, thyroglobulin, chromogranin A and glial fibrillary acidic protein was not detected. This, along with the histological morphology and absence of a primary tumour, was compatible with an ectopic choroid plexus neoplasm. Follow-up performed at 3, 14 and 24 months postoperatively revealed neurological improvement without recurrence. Relevance and novel information We describe the presentation, histopathological and immunohistochemical features and outcome of a case of a rare ectopic choroid plexus neoplasm in the spinal cord of a cat.

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Section: Discussionmentioning

confidence: 62%

Section: Discussionmentioning

confidence: 99%

Spinal ectopic choroid plexus papilloma in a cat

Tabanez¹,

Beck²,

Driver

et al. 2021

Journal of Feline Medicine and Surgery Open Reports

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“…Ectopic choroid plexus rests can be found in the CNS. It has been described within the spinal cord 17 , in the pre-sacral region 10 , in the cerebellopontine angle 11,12 and even associated with a case of trigeminal neuralgia 13 .…”

Section: Discussionmentioning

confidence: 99%

Choroid Plexus in the Central Canal of the Spinal Cord Causing Recurrent Syringomyelia

et al. 2018

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Our illustrative case reveals the presence of CP in the central canal of the spinal cord that may suggest a role in the etiology of recurrent syringomyelia. Although management poses a challenge to neurosurgeons, prompt decompression and shunting of the syringomyelia remains a favorable approach with acceptable outcomes. Further investigation into the pathophysiology of central canal CP ectopic causing recurrent syringomyelia and its correlation with spinal cord development may help future treatments.

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