Ectopic pancreas tissue appearing in a mediastinal cyst

Szabados, S.; Lénárd, László; Tornóczky, Tamás; Várady, Edit; Verzár, Zsófia

doi:10.1186/1749-8090-7-22

Cited by 15 publications

(17 citation statements)

References 6 publications

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“…Alternatively, isolated ectopic pancreas without anatomical or vascular connections to the normal pancreas is extremely rare. To the best of our knowledge, only 20 cases have been reported previously since the first description of this entity in the literature by Shillitoe and Wilson . Clinical presentation is variable, with atypical chest pain and dyspnea most frequently reported.…”

Section: Discussionmentioning

confidence: 99%

Ectopic pancreas in a giant mediastinal cyst

Boven

Jurhill

et al. 2014

Clinical Respiratory J

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Ectopic pancreas located in the mediastium is an extremely rare anomaly. We present a case of an ectopic pancreas located in a giant mediastinal cyst in an 18-year-old man. He presented with symptoms of dyspnea due to external compression of the cyst on the left main bronchus. Complete surgical resection was performed through median sternotomy, with relief of the bronchial compression postoperatively. Literature review showed 20 previously reported cases. These masses were usually large (>10 cm), almost exclusively located in the anterior mediastinum, predominately cystic in nature and generally benign. Surgical resection was performed in all reported cases with a favorable prognosis. Due to the size of these masses, operative treatment can be challenging and should be carefully planned, with specific considerations regarding anesthetic and surgical management.

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Section: Discussionmentioning

confidence: 99%

Ectopic pancreas in a giant mediastinal cyst

Boven

Jurhill

et al. 2014

Clinical Respiratory J

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“…It is presence of pancreatic tissue without anatomic or vascular continuity with the normally developed pancreas. Although it is common to occur intra abdominally from anywhere along distal end of the oesophagus to the colon, it has been reported very rarely in extra abdominal sites such as mediastinal cysts, bronchi, lung, umbilicus and brain [ 6 – 8 ]. Intra-abdominal HP lesions commonly known to occur intestines although fallopian tubes, lymph nodes and spleen were rare sites [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Gastric fundal heterotopic pancreas mimicking a gastrointestinal stromal tumour (GIST): a case report and a brief review

et al. 2016

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BackgroundHeterotopic pancreas is a rare congenital condition characterised by pancreatic tissue lacking vascular or anatomic communication with the normal pancreas. Most cases of ectopic pancreas are asymptomatic. The preoperative diagnosis of this condition is difficult.Case presentationA 50-year-old woman presented with dyspeptic symptoms of 4 years duration. Contrast enhanced CT (computed tomography) scan of abdomen suggested a gastrointestinal stromal tumour in the fundus of the stomach. The patient underwent laparoscopy assisted resection and subsequent histology revealed ectopic pancreatic tissue.ConclusionAlthough heterotopic pancreas is a rare lesion diagnosed on histology, it should be considered in the differential diagnosis of gastric mass lesions and in patients presenting with vague upper gastrointestinal symptoms.

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“…Ectopic pancreatic tissue is an uncommon developmental anomaly and mostly occurs in the gastrointestinal tract [1, 2, 3, 4, 5, 14] and rarely in the mediastinum [11], the gallbladder [10] or the retroperitoneum [9]. This condition is usually asymptomatic and rarely complicated by pancreatitis [4], gastrointestinal tract bleeding [3, 6], perforation [5] or malignant transformation [1, 7, 8], based on anatomical location [1].…”

Section: Discussionmentioning

confidence: 99%

“…Most of the reported cases are located in the stomach or duodenum [1, 2]. The other cases were reported in the lower gastrointestinal tract [1, 2, 3, 4, 5], retroperitoneum [9], biliary system [10] or intrathoracic region [11]. Complete resection of ectopic pancreatic tissue to eliminate the symptoms is the surgical principle [12, 13].…”

Section: Introductionmentioning

confidence: 99%

Laparoscopy-Assisted Billroth I Gastrectomy for Ectopic Pancreas in the Prepyloric Region

Lee¹,

H²,

Guo³

et al. 2012

Case Rep Gastroenterol

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Ectopic pancreatic tissue is an uncommon developmental anomaly. The condition mostly occurs in the gastrointestinal tract and is usually asymptomatic. It rarely causes symptoms of inflammation, bleeding and perforation, and has potential for malignant change. Though it is an uncommon condition, cases of ectopic pancreas have been reported worldwide. Preoperative diagnosis of ectopic pancreas is challenging because of its nonspecific symptoms and signs. Owing to the revolution of minimally invasive surgery, submucosal tumors of the stomach can be resected by laparoscopic techniques. We have earlier reported on a case of ectopic pancreas in the stomach treated by robotics-assisted laparoscopic wedge resection. Herein, we report a case of ectopic pancreas in the prepyloric region of the stomach. A 44-year-old female presented with a two-week history of epigastralgia with radiation to the back. She received endoscopy check-up which disclosed a mass in the stomach. By endoscopic findings, a submucosal lesion in the prepyloric region with umbilical folding on the mucosa was identified. The umbilical folding on the mucosa hint the orifice of the duct of ectopic pancreas into the gastric mucosa suggestive of ectopic pancreas. Contrast-enhanced abdominal computed tomography showed a 5 cm cystic mass with heterogeneous content. To sum it up, the patient was diagnosed as ectopic pancreas in the stomach. She underwent laparoscopy-assisted antrectomy with Billroth I anastomosis (excision of the antrum and prepyloric region with reconstruction of gastrointestinal continuity by gastroduodenostomy) and had an uneventful hospitalization course. The histopathology of the resected tumor demonstrated ectopic pancreatic tissue in the gastric wall. To the best of our knowledge, excision of gastric ectopic pancreas using laparoscopy-assisted antrectomy with Billroth I anastomosis has never been reported in the literature.

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Ectopic pancreas tissue appearing in a mediastinal cyst

Cited by 15 publications

References 6 publications

Ectopic pancreas in a giant mediastinal cyst

Ectopic pancreas in a giant mediastinal cyst

Gastric fundal heterotopic pancreas mimicking a gastrointestinal stromal tumour (GIST): a case report and a brief review

Laparoscopy-Assisted Billroth I Gastrectomy for Ectopic Pancreas in the Prepyloric Region

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