Ectopic ossification in the cranial dura mater in dialysis patients with secondary hyperparathyroidism

Oyama, Yoshihiro; Kazama, Junichiro James; Fukagawa, Masafumi; Arakawa, Yasuaki; Ezuka, Isamu

doi:10.1093/ndtplus/sfp115

Cited by 2 publications

(2 citation statements)

References 12 publications

(12 reference statements)

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“…At this point, it is postulated that this tissue formation is either in response to irritation of the dura mater or is a result of bone re-growth. The initiation of the connective tissue growth from the center of the craniotomy in some of the control cases was not unexpected, as the formation of “bony islands” in the center of cranial defects has been reported by several groups studying bone regeneration (Aronin et al, 2010; Levi et al, 2011; Oyama et al, 2010; Sohn et al, 2010). Additional histological studies comparing tissue re-growth in animals implanted with control windows to that in animals with no windows implanted may be useful in determining the extent of the tissue response that can be attributed to the presence of the cranial window.…”

Section: Discussionmentioning

confidence: 61%

A cranial window imaging method for monitoring vascular growth around chronically implanted micro-ECoG devices

Schendel

Thongpang

Brodnick

et al. 2013

Journal of Neuroscience Methods

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Implantable neural micro-electrode arrays have the potential to restore lost sensory or motor function to many different areas of the body. However, the invasiveness of these implants often results in scar tissue formation, which can have detrimental effects on recorded signal quality and longevity. Traditional histological techniques can be employed to study the tissue reaction to implanted micro-electrode arrays, but these techniques require removal of the brain from the skull, often causing damage to the meninges and cortical surface. This is especially unfavorable when studying the tissue response to electrode arrays such as the micro-electrocorticography (micro-ECoG) device, which sits on the surface of the cerebral cortex. In order to better understand the biological changes occurring around these types of devices, a cranial window implantation scheme has been developed, through which the tissue response can be studied in vivo over the entire implantation period. Rats were implanted with epidural micro-ECoG arrays, over which glass coverslips were placed and sealed to the skull, creating cranial windows. Vascular growth around the devices was monitored for one month after implantation. It was found that blood vessels grew through holes in the micro-ECoG substrate, spreading over the top of the device. Micro-hematomas were observed at varying time points after device implantation in every animal, and tissue growth between the micro-ECoG array and the window occurred in several cases. Use of the cranial window imaging technique with these devices enabled the observation of tissue changes that would normally go unnoticed with a standard device implantation scheme.

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Section: Discussionmentioning

confidence: 61%

A cranial window imaging method for monitoring vascular growth around chronically implanted micro-ECoG devices

Schendel

Thongpang

Brodnick

et al. 2013

Journal of Neuroscience Methods

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“…Regarding susceptibility to pathological calcification, Oyama et al [ 42 ] reported a case of ectopic ossification in the cranial dura mater in a dialysis patient with secondary hyperparathyroidism. In this case, significant calcification was only noted at the tentorium cerebelli and falx cerebri, while the dura mater of the convexity was free from pathological calcification.…”

Section: Diversity In the Classifications Of Davfsmentioning

confidence: 99%

Embryological Consideration of Dural AVFs in Relation to the Neural Crest and the Mesoderm

Tanaka

2019

Neurointervention

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Intracranial and spinal dural arteriovenous fistulas (DAVFs) are vascular pathologies of the dural membrane with arteriovenous shunts. They are abnormal communications between arteries and veins or dural venous sinuses that sit between the two sheets of the dura mater. The dura propria faces the surface of brain, and the osteal dura faces the bone. The location of the shunt points is not distributed homogeneously on the surface of the dural membrane, but there are certain areas susceptible to DAVFs. The dura mater of the olfactory groove, falx cerebri, inferior sagittal sinus, tentorium cerebelli, and falx cerebelli, and the dura mater at the level of the spinal cord are composed only of dura propria, and these areas are derived from neural crest cells. The dura mater of the cavernous sinus, transverse sinus, sigmoid sinus, and anterior condylar confluence surrounding the hypoglossal canal are composed of both dura propria and osteal dura; this group is derived from mesoderm. Although the cause of this heterogeneity has not yet been determined, there are some specific characteristics and tendencies in terms of the embryological features. The possible reasons for the segmental susceptibility to DAVFs are summarized based on the embryology of the dura mater.

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Ectopic ossification in the cranial dura mater in dialysis patients with secondary hyperparathyroidism

Cited by 2 publications

References 12 publications

A cranial window imaging method for monitoring vascular growth around chronically implanted micro-ECoG devices

A cranial window imaging method for monitoring vascular growth around chronically implanted micro-ECoG devices

Embryological Consideration of Dural AVFs in Relation to the Neural Crest and the Mesoderm

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