Ectopic lingual thyroid

Reddy, Preethi M.; Reddy, K Krishna Mohan; Reddy, Ramesh; Babu, L

doi:10.4103/0976-6944.118542

Cited by 8 publications

(9 citation statements)

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“…Ectopia occurs during descent of the thyroid from the foramen caecum to the normal position, as a result of maternal antibodies inhibiting thyroid antigens or persistent thyroglossal ductal epithelial tissue (3)(4)(5). An ectopic thyroid occurs in 1 in 100,000-300,000 people (2-4).…”

Section: Discussionmentioning

confidence: 99%

“…It is often asymptomatic, and the most common symptoms are due to growth of the lingual thyroid tissue (3,4). This growth can occur as a result of metabolic stresses, including puberty, pregnancy, trauma, or menopause (4,5). A lingual thyroid can cause symptoms such as a cough, snoring, awareness of a foreign body, sleep apnea, dysphagia, dysphonia, and stomatolalia (3,4).…”

Section: Discussionmentioning

confidence: 99%

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Incidental Lingual Thyroid Informs Surgery

Goode

McKellar

Carter

et al. 2014

Journal of Nuclear Medicine Technology

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Incidental Lingual Thyroid Informs Surgery

Goode

McKellar

Carter

et al. 2014

Journal of Nuclear Medicine Technology

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show abstract

“…Derivatives were able to counteract EGFinduced EGFR phosphorylation and showed better or at least comparable potency with respect to PD153035 of which the following compound was promising [64]. Several N-methyl-4-(4-methoxyanilino) quinazolines (51) and stated that substitution at the 5-,6-,7-positions of the quinazoline and replacement of the quinazoline by other nitrogen-containing heterocycles. Replacement of the quinazoline ring with a quinoline, a benzo[d][1,2,3]triazine, or an isoquinoline ring showed that the nitrogen at the 1-position is important for activity, while the carbon at the 2-positioncan be replaced by a nitrogen and thenitrogen at the 3-position can be replaced by a carbon.…”

Section: Compound 45 R=cooh R1= P-c6h5mentioning

confidence: 99%

“…Some of these compounds have been found to exhibit good antifungal activity [51]. A condensation of four defferent 3-formylchromones with 2-methyl/phenyl-3-amino-4(3H)-quinazolinone and their dibromo analogs have been characterized as their respective 3-[N-(4-oxo-2-methyl/phenyl-3-quinazolinyl)-formimidoyl]-chromones (38).…”

Section: Compound 34mentioning

confidence: 99%

A Review on a Highly Important Hetrocycle Quinazolinone Compounds and their Diverse Biological Activities

2016

European Reviews of Chemical Research

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Quinazolinone and their derivatives have been studied extensively for various biological activities such as anti-inflammatory, antimicrobial, anticancer, anticonvulsant and anti-HIV activity etc. The purpose of this review was to collate literature work reported by researchers on quinazoline for their various pharmacological activities. Quinazolinone derivatives are one of the most active classes of compounds possessing a wide spectrum of biological activity. Recently several scientists have been reported that introduction of various heterocyclic moieties at quinazolinone nucleus modulate the activity. Various derivatives of quinazolinone have been synthesized and evaluated for their biological activities. This review might be helpful in the development of these novel lead molecules to potential drug candidates for future prospect.Keywords: Quinazoline, antimicrobial, Anti HIV, Anti cancer, biologically active. IntroductionHeterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, heterocyclic structures form the basis of many pharmaceutical, agrochemical and veterinary products. Quinazoline (1) are classes of fused heterocycles that are of considerable interest because of the diverse range of their biological activities such as, antimicrobial, anticancer, anticonvulsant, anti-tubercular, etc [1][2][3][4][5]. Quinazolin is a heterocyclic compound consists of two fused six membered simple aromatic rings, a benzene ring and a pyrimidine ring. The quinazolin nucleus has attracted the attention of medicinal chemists due to its well known anticancer activity, and many substituted quinazolin derivatives have recently earned great interest in chemotherapy as antitumor drugs [6]. Pharmacologically quinazolin particularly quinazolin-4-one (2) or quinazolinone are the most important classes of heterocyclic compounds. Quinazolin-4-one is synthesized when the keto group is introduced in the pyrimidine ring of quinazolin. Quinazolinone compounds possess versatile biological activities; such as anticancer [7][8]

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“…Mora et al [17] determined the presence of the nematicide aldicarb and its metabolites aldicarb sulphoxide and aldicarb sulphone in soils and potatoes by liquid chromatography with photodiode array detection. Although there are reports in the literature for several methods of determinations of pesticides, there are few focused on electrochemical methods; hence, in this investigation, electrochemical determinations [18][19][20] were employed.…”

Section: Aldicarb (C 7 H 14 N 2 O 2 S)mentioning

confidence: 99%