Ectopic Craniopharyngioma

Ectopic Occurrence of Craniopharyngiomas

“…Fifteen months later, the patient was noted to have a second lesion adjacent to the site of the previous craniotomy. The lesion proved to be an adamantinomatous craniopharyngioma like the one that had been previously removed (Kordes et al, 2011). Other case reports have documented similar seeding of tumor cells distant from the original tumor site along the surgical path (Ragoowansi and Piepgras, 1991;Lee et al, 1999;Novegno et al, 2002;Ishii et al, 2004;Kawaguchi et al, 2005;Jeong et al, 2006;Yamada et al, 2006;Bikmaz, 2009;Elliott, 2009;Romani et al, 2010;Blank, 2011;Elfving et al, 2011;Jakobs and Orakcioglu, 2012).…”

Craniopharyngioma – Pediatric Management

“…Many authors take a critical view of planned radical resection in these cases because of the risk of surgically induced deficits (mainly hypothalamic), and the high rate of recurrence in infants and small children despite apparently complete resection (Muller, 2006(Muller, , 2006b. Recurrences at ectopic localizations are reported (Kordes et al, 2011). Whereas following incomplete resection the residual tumor shows progression in 71 to 90% of patients, the rate of progression after incomplete resection followed by radiotherapy is 21% (Becker et al, 1999).…”

Management of the Recurrence of Craniopharyngiomas

“…Most were of the adamantinous histological subtype. These recurrences are thought to arise from contamination of tumor cells along the surgical tract during the primary transcranial resection, or by spreading through CSF pathways into distant locations of the subarachnoid space (Elliott et al, 2009;Kordes et al, 2011;Jakobs and Orakcioglu, 2012). In general, these ectopic lesions should be treated with curative intent, especially when found in isolation.…”