Ectopic brain tissue in the orbit

Abstract

The mass must be considered a rare example of heterotopic brain tissue in the orbit and is the only instance we could find in the literature in which a formed eye was absent but in which a scattered primitive ocular structure could be identified.

Primary Orbital Cystic Pilocytic Astrocytoma

“…There have been several previous case reports documenting heterotopic/ectopic brain in the orbit [7,8,9,10], but none of those displayed features of a pilocytic astrocytoma. We examined the whole specimen as several slices and could not detect any non-neoplastic brain tissue with calcospheres (commonly observed in heterotopic brain) [7,8,9,10].…”

“…One possibility is that brain heterotopia occurred during development, with subsequent sequestration and anatomic discontinuity [7,8,9,10]. This would have been followed by tumour development with effacement of all heterotopic brain tissue.…”

“…Another diagnosis meriting consideration includes a congenital cystic eye and microphthalmia with cyst [10]. However, this can be confidently excluded by the presence of an anatomically intact globe at birth and during the surgical procedure.…”

“…We examined the whole specimen as several slices and could not detect any non-neoplastic brain tissue with calcospheres (commonly observed in heterotopic brain) [7,8,9,10]. …”

Tecido cerebral ectópico na órbita: relato de dois casos

“…Wilkins et al 4 , em 1987, relataram um terceiro caso de tecido cerebral ectópico na órbita com conteúdo líquido. Posteriormente, Elder et al 5 em 1989, Hingorani et al 6 em 1997, Scheiner et al 7 em 1999 e Harmon et al 8 em 2000, também registraram casos de tecido cerebral ectópico na órbita. Não se conhece nenhum caso descrito na literatura oftalmológica nacional.…”