“…Cosms also include dynamic interactions between and among species so that potential "ecosystem-level" effects can be evaluated, including predator-prey interactions in the larger systems (Giesy and Geiger 1980 ). Early cosm studies of CPY were reviewed by Leeuwangh ( 1994 ), Barron and Woodburn ( 1995 ), and Giesy et al ( 1999 ). Since the publication of the Giesy et al review, results of several cosm studies of CPY have featured prominently in comparisons of cosm studies, single-species laboratory toxicity tests, and regulatory benchmarks across classes of insecticides (Brock et al 2000(Brock et al , 2006Maltby et al 2005 ;van Wijngaarden et al 2005b ).…”