Ecotoxicity of silica nanoparticles to the green alga <i>pseudokirchneriella subcapitata</i>: Importance of surface area

Hoecke, Karen Van; Schamphelaere, Karel A.C. De; Meeren, Paul Van der; Lucas, Stéphane; Janssen, Colin R.

doi:10.1897/07-634.1

Cited by 209 publications

(131 citation statements)

References 30 publications

Supporting

Mentioning

114

Contrasting

Unclassified

Order By: Relevance

“…Auffan et al [49] showed that the toxicity of cerium oxide NPs to human fibroblast cells was higher for NPs compared with bulk particles on a mass basis but similar on a surface-areanormalized basis. Furthermore, surface area was an important predictor for toxicity of silica NPs with algae [50]. However, the importance of NP surface area to toxicity for CNPs in ecotoxicity tests is presently unknown, and surface area has not yet been related to any in vivo ecotoxicological effects for CNPs to our knowledge.…”

Section: Steps In Conducting Ecotoxicity Tests With Cnpsmentioning

confidence: 96%

Methodological considerations for testing the ecotoxicity of carbon nanotubes and fullerenes: Review

Petersen

Henry

2011

Enviro Toxic and Chemistry

114

View full text Add to dashboard Cite

Abstract-The recent emergence of manufactured nanoparticles (NPs) that are released into the environment and lead to exposure in organisms has accelerated the need to determine NP toxicity. Techniques for measuring the toxicity of NPs (nanotoxicology) in ecological receptors (nanoecotoxicology) are in their infancy, however, and establishing standardized ecotoxicity tests for NPs are presently limited by several factors. These factors include the extent of NP characterization necessary (or possible) before, during, and after toxicity tests such that toxic effects can be related to physicochemical characteristics of NPs; determining uptake and distribution of NPs within exposed organisms (does uptake occur or are effects exerted at organism surfaces?); and determining the appropriate types of controls to incorporate into ecotoxicity tests with NPs. In this review, the authors focus on the important elements of measuring the ecotoxicity of carbon NPs (CNPs) and make recommendations for ecotoxicology testing that should enable more rigorous interpretations of collected data and interlaboratory comparisons. This review is intended to serve as a next step toward developing standardized tests that can be incorporated into a regulatory framework for CNPs. Environ. Toxicol. Chem.

show abstract

Section: Steps In Conducting Ecotoxicity Tests With Cnpsmentioning

confidence: 96%

Methodological considerations for testing the ecotoxicity of carbon nanotubes and fullerenes: Review

Petersen

Henry

2011

Enviro Toxic and Chemistry

114

View full text Add to dashboard Cite

show abstract

“…One of the earlier studies using the green algae Desmodesmus subspicatus found no statistically significant differences associated with irradiation before TiO 2 NP (25 and 100 nm) exposures, nor an effect of shading [51]. Similarly, Van Hoecke et al [52] found no effects of shading on Pseudokirchneriella subcapitata during experiments with CeO 2 NPs. Aruoja et al [53] reported a similar view for CuO and ZnO NP.…”

Section: Critical Variations In Protocols For the Microalgae Testmentioning

confidence: 90%

Ecotoxicity test methods for engineered nanomaterials: Practical experiences and recommendations from the bench

Handy

Cornelis

Fernandes

et al. 2011

Enviro Toxic and Chemistry

297

236

View full text Add to dashboard Cite

Abstract-Ecotoxicology research is using many methods for engineered nanomaterials (ENMs), but the collective experience from researchers has not been documented. This paper reports the practical issues for working with ENMs and suggests nano-specific modifications to protocols. The review considers generic practical issues, as well as specific issues for aquatic tests, marine grazers, soil organisms, and bioaccumulation studies. Current procedures for cleaning glassware are adequate, but electrodes are problematic. The maintenance of exposure concentration is challenging, but can be achieved with some ENMs. The need to characterize the media during experiments is identified, but rapid analytical methods are not available to do this. The use of sonication and natural/synthetic dispersants are discussed. Nano-specific biological endpoints may be developed for a tiered monitoring scheme to diagnose ENM exposure or effect. A case study of the algal growth test highlights many small deviations in current regulatory test protocols that are allowed (shaking, lighting, mixing methods), but these should be standardized for ENMs. Invertebrate (Daphnia) tests should account for mechanical toxicity of ENMs. Fish tests should consider semistatic exposure to minimize wastewater and animal husbandry. The inclusion of a benthic test is recommended for the base set of ecotoxicity tests with ENMs. The sensitivity of soil tests needs to be increased for ENMs and shortened for logistics reasons; improvements include using Caenorhabditis elegans, aquatic media, and metabolism endpoints in the plant growth tests. The existing bioaccumulation tests are conceptually flawed and require considerable modification, or a new test, to work for ENMs. Overall, most methodologies need some amendments, and recommendations are made to assist researchers. Environ. Toxicol. Chem. 2012;31:15-31. # 2011 SETAC

show abstract

“…Agglomeration is very important for all ENPs, especially for aquatic tests with TiO 2 and CeO 54, 60, 145, 154. In practice it is difficult to maintain a stable suspension of these particles in the media.…”

Section: Discussionmentioning

confidence: 99%

Aquatic Ecotoxicity Testing of Nanoparticles—The Quest To Disclose Nanoparticle Effects

et al. 2016

View full text Add to dashboard Cite

The number of products on the market containing engineered nanoparticles (ENPs) has increased significantly, and concerns have been raised regarding their ecotoxicological effects. Environmental safety assessments as well as relevant and reliable ecotoxicological data are required for the safe and sustainable use of ENPs. Although the number of publications on the ecotoxicological effects and uptake of ENPs is rapidly expanding, the applicability of the reported data for hazard assessment is questionable. A major knowledge gap is whether nanoparticle effects occur when test organisms are exposed to ENPs in aquatic test systems. Filling this gap is not straightforward, because of the broad range of ENPs and the different behavior of ENPs compared to “ordinary” (dissolved) chemicals in the ecotoxicity test systems. The risk of generating false negatives, and false positives, in the currently used tests is high, and in most cases difficult to assess. This Review outlines some of the pitfalls in the aquatic toxicity testing of ENPs which may lead to misinterpretation of test results. Response types are also proposed to reveal potential nanoparticle effects in the aquatic test organisms.

show abstract

Ecotoxicity of silica nanoparticles to the green alga pseudokirchneriella subcapitata: Importance of surface area

Cited by 209 publications

References 30 publications

Methodological considerations for testing the ecotoxicity of carbon nanotubes and fullerenes: Review

Methodological considerations for testing the ecotoxicity of carbon nanotubes and fullerenes: Review

Ecotoxicity test methods for engineered nanomaterials: Practical experiences and recommendations from the bench

Aquatic Ecotoxicity Testing of Nanoparticles—The Quest To Disclose Nanoparticle Effects

Contact Info

Product

Resources

About