Economical Second-Order Designs Based on Irregular Fractions of the 3ⁿFactorial

Optimised amylases extraction from oat seeds and its impact on bread properties

“…This approach explores the response surfaces covered in the experimental design, thus it makes the optimisation process more efficient and effective [17]. The most frequent designs in optimisation problems involving three or more factors are central composite designs, D-optimal designs, and others, such as Box-Behnken designs [18][19][20]. Central composite and Box-Behnken designs are the most appropriate to detect curvatures in a multidimensional space.…”