Entrepreneurship is an innovative risky business during the phases of the life cycle of origin and growth -to conquer the market by better satisfying consumer needs for entrepreneurial income. Innovative risk business is in organic relationship with the routine type of business in the phases of maturity and decline, designed to keep the market and ensure the return on investment. The motivation for entrepreneurship is, in essence, the motivation for innovative activity for the delivery of new goods and services to the market. A favorable entrepreneurial climate created within the framework of state regulation and entrepreneurship support with the aim of producing competitive products, import substitution, increasing export potential, and economic growth is an institutional condition for business revitalization. Business development on the basis of state regulation and support of entrepreneurship forms a certain model, consisting of a set of organizational and economic blocks: management entities, management objects (business enterprises), measures of state regulation and support of entrepreneurship in four types, management methods and tools, costs of creating a favorable business climate, socioeconomic benchmarks, entrepreneurship activity, socio-economic indicators of business activity and monitoring the state of society. The blocks of the model, interacting with each other, lead the entrepreneurial business to the desired state, determined by the totality of socio-economic landmarks.