Economic Evaluation of Uterine Artery Embolization versus Hysterectomy in the Treatment of Symptomatic Uterine Fibroids: Results from the Randomized EMMY Trial

Uterine artery embolization versus surgery for symptomatic uterine fibroids: a randomized controlled trial and a meta-analysis of the literature

“…With our search criterion, 107 individual records were found, but 13 publications [5][6][7][8][9][16][17][18][19][20][21][22][23] were Wnally included. Hehenkamp WJ et al study and other seven articles reported diVerent kinds of data in the same RCT, the randomized EMMY trial [6,[16][17][18][19][21][22][23].…”

“…Hehenkamp WJ et al study and other seven articles reported diVerent kinds of data in the same RCT, the randomized EMMY trial [6,[16][17][18][19][21][22][23]. Mara et al [7,20] and another study reported the RCT, thus the most recent publication was included in the analysis.…”

The direct and indirect costs of uterine fibroid tumors: a systematic review of the literature between 2000 and 2013

“…Volkers et al's analysis adopted a societal perspective, which represents the national health care payer's perspective. 23 Table 3 summarizes 14 studies that reported surgery and inpatient costs of UF. Table 4 and Table 5 summarize studies that reported outpatient and drug costs, respectively.…”

“…[23][24][25][26][27][28][29][30][31][32][33][34][35] Within each of these studies, the total direct costs among different procedures (e.g., hysterectomy, myomectomy, and embolization) did not differ substantially. Total direct costs within 1 year of UF-related surgeries ranged from $15,878 to $21,603 per patient in the U.S. 25,28,33 Volkers et al reported $9,076 per patient for UAE and $11,028 per patient for hysterectomy over 2 years of follow-up after surgery in the Netherlands.…”

An Update on Magnetic Resonance Guided Focused Ultrasound Surgery (MRgFUS) of Uterine Fibroids

“…UAE has a lower rate of major complications than hysterectomy or myomectomy, albeit with a higher rate of minor complications. Two large European studies, the multicenter randomized EMbolization versus hysterectomY (EMMY) trial [16] and the HOPEFUL study [17] found that from a societal economic perspective, UAE is the superior treatment strategy to hysterectomy in women with symptomatic uterine fibroids, although the need to improve the management of expectations following UAE, particularly regarding fertility, was emphasized.…”