Economic Evaluation of the Dr. Bart Application in Individuals With Knee and/or Hip Osteoarthritis

Pelle, T.; Bevers, K.; Hoogen, Frank van den; Palen, Job van der; Ende, Cornelia van den

doi:10.1002/acr.24608

Cited by 5 publications

(35 citation statements)

References 43 publications

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“…Overall, the 18 studies in this review were conducted between 2016 and 2022. Of the 18 studies, 10 (56%) [30][31][32][33][34][35][36][37][38][39] were conducted in the United States; 2 (11%) [40,41] in the Netherlands; 2 (11%) [42,43] in Sweden; 1 (6%) [44] in Germany; 1 (6%) [45] in Japan; 1 (6%) [46] in the United Kingdom; and 1 (6%) [47] jointly in the Netherlands, Spain, and Taiwan. Furthermore, of the 18 studies, 10 (56%) [30][31][32][34][35][36][37][38][39]45] were industry funded, 6 (33%) [40,41,43,44,46,47] were publicly funded, and the remaining 2 (11%) [33,42] received mixed funding.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Regarding the type of EE performed, of the 18 studies, 7 (39%) [30][31][32][33][34][35][36] involved nonrandomized study-based EE, 6 (33%) [37][38][39]44,45,47] involved model-based EE, and 5 (28%) [40][41][42][43]46] involved RCT-based EE. Of the 18 studies, 12 (67%) used a payer perspective [30][31][32][33][34][35][36]38,39,41,45,46], whereas 6 (33%) used a societal perspective [37,40,[42][43][44]47], with 2 (11%) of the latter group also taking a payer perspective [37,47]. The time horizon used for the EE was between 6 and 12 months for 56% (10/18) of the studies [32][33][34][35][36][40][41][42][43]46]…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Of the 18 studies, 12 (67%) used a payer perspective [30][31][32][33][34][35][36]38,39,41,45,46], whereas 6 (33%) used a societal perspective [37,40,[42][43][44]47], with 2 (11%) of the latter group also taking a payer perspective [37,47]. The time horizon used for the EE was between 6 and 12 months for 56% (10/18) of the studies [32][33][34][35][36][40][41][42][43]46], 24 months for 6% (1/18) of the studies [31], 36 months for 17% (3/18) of the studies [30,38,44], 60 months for 6% (1/18) of the studies [47], 120 months for 6% (1/18) of the studies [39], and lifetime for 11% (2/11) of the studies [37,45]. The intervention group sample sizes ranged between 60 and 305 participants for RCT-based EE and between 248 and 4790 participants for nonrandomized study-based EE.…”

Section: Study Characteristicsmentioning

confidence: 99%

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Economic Evaluation Associated With Clinical-Grade Mobile App–Based Digital Therapeutic Interventions: Systematic Review

Sapanel¹,

Tadeo²,

Brenna³

et al. 2023

J Med Internet Res

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Background Digital therapeutics (DTx), a class of software-based clinical interventions, are promising new technologies that can potentially prevent, manage, or treat a spectrum of medical disorders and diseases as well as deliver unprecedented portability for patients and scalability for health care providers. Their adoption and implementation were accelerated by the need for remote care during the COVID-19 pandemic, and awareness about their utility has rapidly grown among providers, payers, and regulators. Despite this, relatively little is known about the capacity of DTx to provide economic value in care. Objective This study aimed to systematically review and summarize the published evidence regarding the cost-effectiveness of clinical-grade mobile app–based DTx and explore the factors affecting such evaluations. Methods A systematic review of economic evaluations of clinical-grade mobile app–based DTx was conducted following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020 guidelines. Major electronic databases, including PubMed, Cochrane Library, and Web of Science, were searched for eligible studies published from inception to October 28, 2022. Two independent reviewers evaluated the eligibility of all the retrieved articles for inclusion in the review. Methodological quality and risk of bias were assessed for each included study. Results A total of 18 studies were included in this review. Of the 18 studies, 7 (39%) were nonrandomized study–based economic evaluations, 6 (33%) were model-based evaluations, and 5 (28%) were randomized clinical trial–based evaluations. The DTx intervention subject to assessment was found to be cost-effective in 12 (67%) studies, cost saving in 5 (28%) studies, and cost-effective in 1 (6%) study in only 1 of the 3 countries where it was being deployed in the final study. Qualitative deficiencies in methodology and substantial potential for bias, including risks of performance bias and selection bias in participant recruitment, were identified in several included studies. Conclusions This systematic review supports the thesis that DTx interventions offer potential economic benefits. However, DTx economic analyses conducted to date exhibit important methodological shortcomings that must be addressed in future evaluations to reduce the uncertainty surrounding the widespread adoption of DTx interventions. Trial Registration PROSPERO International Prospective Register of Systematic Reviews CRD42022358616; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022358616

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Section: Study Characteristicsmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

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Economic Evaluation Associated With Clinical-Grade Mobile App–Based Digital Therapeutic Interventions: Systematic Review

Sapanel¹,

Tadeo²,

Brenna³

et al. 2023

J Med Internet Res

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“…As such, this method allows delivery of support to patients who may not otherwise have had access to these behavioural interventions. Further, digital interventions in OA have been shown to be cost-effective compared to usual care [13].…”

Section: Introductionmentioning

confidence: 99%

Acceptability and preliminary effectiveness of a single-arm 12-week digital behavioral health intervention in patients with knee osteoarthritis

Godziuk

Prado

Quintanilha

et al. 2023

BMC Musculoskelet Disord

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Background Digital health interventions may improve osteoarthritis (OA) management. This study evaluated the acceptability and preliminary effectiveness of a multimodal digital nutrition, exercise, and mindfulness intervention in adults with knee OA. Methods Adults with advanced knee OA and an orthopaedic referral were invited to self-enroll in a pragmatic 12-week single-arm intervention. OA-focused nutrition and exercise resources were delivered weekly by email, and secondary components accessed on-demand (web-platform, webinars, and nutrition consultation). Acceptability was assessed by qualitative interview data and completion rates. Preliminary effectiveness on clinical outcomes was assessed by change in health-related quality of life, well-being, mindfulness, self-efficacy, and interest in total knee arthroplasty (TKA) between baseline and 12-weeks. Results N = 102 patients self-enrolled (73.5% female, age 64 ± 7 years, body mass index 32.9 ± 7.3 kg/m2); n = 53 completed the 12-week intervention (71.7% female, age 65 ± 7 years, body mass index 33.4 ± 6.3 kg/m2). Acceptability was demonstrated by positive perceptions of tailored intervention resources. In study completers, health-related quality of life components of pain and physical functioning domains improved at 12-weeks [change in SF36 4.4 (95%CI 0.2–8.6), p = 0.016, and 6.7 (95%CI 2.7–10.7), p < 0.001, respectively]. Self-efficacy for managing daily activities improved [change in PROMIS T-score 4.4 (95%CI 2.8–6.0), p < 0.001]. Conclusion A 12-week digital multimodal intervention for knee OA was acceptable to patients and shows preliminary effectiveness in improving self-efficacy, aspects of quality of life, and decreasing interest in TKA. Digital behavioral interventions for knee OA may be an acceptable approach to improve patient outcomes and OA self-management while potentially reducing utilization of costly health system resources.

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“…Furthermore, patients who have geographical barriers to accessing medical care, such as those living in mountainous or rural areas, can receive medical care at home, thus reducing the need for hospital visits and potentially reducing medical costs [ 8 ]. If mHealth is proven useful and becomes widely adopted, it will allow more patients to enjoy high-quality and consistent medical care [ 9 ]. In addition, in the setting of a global pandemic caused by a new infectious disease, contact with others can be minimized; thus, mHealth is also expected to play a role in infection control.…”

Section: Introductionmentioning

confidence: 99%

mHealth for the Self-management of Knee Osteoarthritis: Scoping Review

Kitagawa¹,

Hayashi²

2023

J Med Internet Res

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Background Educating patients on the self-management of knee osteoarthritis (OA) reportedly reduces pain, improves activities of daily living, and even reduces health care costs. Objective This scoping review will summarize the current evidence on mobile health (mHealth) and smartphone app–based disease self-management for patients with knee OA. Methods PubMed, Web of Science, the Cochrane Central Register of Controlled Trials, and CINAHL were systematically searched in May 2021 using the keywords “knee osteoarthritis,” “mobile health,” and “self-management.” Studies that investigated patients with knee OA based on radiography or clinical diagnosis were included. The following criteria were applied to the mobile phone apps included in the search-derived studies: the ability to (1) record and manage symptoms, (2) provide patient education, and (3) guide and record activities of daily living. Studies eligible for inclusion in this scoping review were interventional trials or observational studies published in English. Results This scoping review included 8 reports, of which 3 were randomized controlled trials and 1 was a conference abstract. Most studies provided data on the outcomes of pain, physical function, and quality of life. Conclusions An increasing number of reports are addressing the effectiveness of mHealth in patients with knee OA, and the data suggest that mHealth efficacy is similar to conventional management of health. International Registered Report Identifier (IRRID) RR2-10.17504/protocols.io.buuxnwxn

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Economic Evaluation of the Dr. Bart Application in Individuals With Knee and/or Hip Osteoarthritis

Cited by 5 publications

References 43 publications

Economic Evaluation Associated With Clinical-Grade Mobile App–Based Digital Therapeutic Interventions: Systematic Review

Economic Evaluation Associated With Clinical-Grade Mobile App–Based Digital Therapeutic Interventions: Systematic Review

Acceptability and preliminary effectiveness of a single-arm 12-week digital behavioral health intervention in patients with knee osteoarthritis

mHealth for the Self-management of Knee Osteoarthritis: Scoping Review

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