Economic Evaluation of Early Interventions for Autistic Children: A Scoping Review

Pye, Katherine; Jackson, Hannah; Iacono, Teresa; Shiell, Alan

doi:10.1007/s10803-023-05938-3

Cited by 1 publication

(3 citation statements)

References 47 publications

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“…There have only been two previous economic evaluation studies alongside a trial that examined early interventions for autistic children (Pye et al, 2023). One intervention (a social-communication program for parents in the UK) was deemed not cost-effective when provided in addition to usual care (Byford et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

“…This study has some key strengths and limitations. While previous economic evaluation studies of treatment interventions for autistic children have mainly used modelling techniques (Pye et al, 2023;Sampaio et al, 2021), we were able to collect cost-effectiveness data alongside effectiveness data. However, the follow-up period of 6 month employed in the trial may be considered as short, where long-term costs of outcomes remain unknown.…”

Section: Strengths and Limitationsmentioning

confidence: 99%

“…Economic evaluation is defined as a comparative analysis of alternative courses of action in terms of both their costs and consequences (Drummond et al, 2015). To date, there is a lack of evidence on the cost-effectiveness of treatments for autistic children and adolescents (Pye et al, 2023;Sampaio et al, 2021). This may be driven by unaddressed challenges in conducting economic evaluations of autism interventions related to diversity of autism presentation, and difficulty with measuring costs and outcomes, including measurement of family effects (Tsiplova & Ungar, 2023).…”

Section: Introductionmentioning

confidence: 99%

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Sleeping Sound Autism Spectrum Disorder (ASD): Cost-Effectiveness of a Brief Behavioural Sleep Intervention in Primary School-Aged Autistic Children

Engel,

Chiotelis,

Papadopoulos

et al. 2024

J Autism Dev Disord

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Disordered sleep is common in autistic children. This study aimed to evaluate the cost-effectiveness of a brief behavioural sleep intervention, the ‘Sleeping Sound intervention’, in primary school-aged autistic children in Australia. A cost-effectiveness analysis was undertaken alongside a randomised controlled trial over a 6-month follow-up period from both a societal and healthcare sector perspective. Resources used by participants were collected from a resource-use questionnaire and administrative data; intervention costs were determined from study records. Mean costs and quality-adjusted life-years (QALYs) were compared between the intervention and treatment as usual (TAU) groups. Uncertainty analysis using bootstrapping and sensitivity analyses were conducted. The sample included 245 children, with 123 participants randomised to the intervention group and 122 to TAU. The mean total costs were higher for the Sleeping Sound intervention with a mean difference of A$745 (95% CI 248; 1242; p = 0.003) from a healthcare sector perspective and A$1310 (95% CI 584; 2035, p < 0.001) from a societal perspective. However, the intervention also resulted in greater QALYs compared with TAU, with a mean difference of 0.038 (95% CI 0.004; 0.072; p = 0.028). The incremental cost-effectiveness ratio was A$24,419/QALY (95% CI 23,135; 25,703) from a healthcare sector perspective and A$41,922/QALY (95% CI 39,915; 43,928) from a societal perspective; with a probability of being cost-effective of 93.8% and 74.7%, respectively. Findings remained robust in the sensitivity analyses. The Sleeping Sound intervention offers a cost-effective approach in improving sleep in primary school-aged autistic children.Trial registration The trial was registered with the International Trial Registry (ISRCTN14077107).

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Section: Discussionmentioning

confidence: 99%

Section: Strengths and Limitationsmentioning

confidence: 99%