2020
DOI: 10.1001/jamanetworkopen.2020.8931
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Economic Burden of Postoperative Neurocognitive Disorders Among US Medicare Patients

Abstract: IMPORTANCE Postoperative neurocognitive disorders (PNDs) after surgical procedures are common and may be associated with increased health care expenditures. OBJECTIVE To quantify the economic burden associated with a PND diagnosis in 1 year following surgical treatment among older patients in the United States. DESIGN, SETTING, AND PARTICIPANTS This retrospective cohort study used claims data from the Bundled Payments for Care Improvement Advanced Model from 4285 hospitals that submitted Medicare Fee-for-servi… Show more

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Cited by 67 publications
(60 citation statements)
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“…POCD is common among the elderly and places an additional burden on patients’ family members and caregivers. The incidence of cognitive dysfunction ranges from 10 to 65% and varies with many factors such as age, education level, sex, comorbidities, type of surgery, and evaluation methods ( Boone et al, 2020 ).…”
Section: Postoperative Cognitive Dysfunctionmentioning
confidence: 99%
“…POCD is common among the elderly and places an additional burden on patients’ family members and caregivers. The incidence of cognitive dysfunction ranges from 10 to 65% and varies with many factors such as age, education level, sex, comorbidities, type of surgery, and evaluation methods ( Boone et al, 2020 ).…”
Section: Postoperative Cognitive Dysfunctionmentioning
confidence: 99%
“…Significant negative outcomes associated with postoperative delirium include falls, immobilisation, institutionalisation, prolonged hospitalisation, mortality, and increased healthcare costs. 3 Long-term preoperative use of zolpidem significantly increased the incidence of delirium, especially at higher doses in this study.…”
mentioning
confidence: 46%
“…These patients may experience a range of symptoms, including delirium, confusion, inattention, and cognitive deficits, that can persist for days to months ( Evered et al, 2018 ). The incidence of PNDs is remarkably high, ranging from 10 to 60%; and these disorders are associated with poor long-term outcomes, increased healthcare costs, loss of independence, and increased mortality ( Witlox et al, 2010 ; Moskowitz et al, 2017 ; Sprung et al, 2017 ; Boone et al, 2020 ). Few effective prevention and treatment strategies are currently available ( Berger et al, 2018 ; Mahanna-Gabrielli et al, 2019 ).…”
Section: Introductionmentioning
confidence: 99%