Economic analysis of the costs associated with prematurity from a literature review

Soilly, Anne-Laure; Lejeune, Catherine; Quantin, Catherine; Béjean, Sophie; Gouyon, Jean‐Bernard

doi:10.1016/j.puhe.2013.09.014

Cited by 47 publications

(36 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The association was unaffected by differences in state-level income, unemployment and poverty levels as well as a variety of individual-level clinical, social and demographic characteristics. If our results were confirmed, these findings suggest approximately 35,800 preterm births each year might be attributable to increasing income inequality, representing a significant economic burden given the immediate and long-term health consequences of prematurity [33]. Given the ubiquity of macro-level exposures such as income inequality [3], further research on their potentially broad population health impact utilizing samples drawn from varying sociopolitical contexts and more recent years may help inform efforts to promote socioeconomic equity and improve population health.…”

Section: Discussionmentioning

confidence: 74%

Preterm Birth in the Context of Increasing Income Inequality

Wallace

Mendola

Chen

et al. 2015

Matern Child Health J

View full text Add to dashboard Cite

Objective Preterm birth is a leading cause of infant morbidity and mortality. Little is known about the contextual effect of US income inequality on preterm birth, an issue of increasing concern given that the current economic divide is the largest since 1928. Methods We examined changes in inequality over time in relation to preterm birth among singleton deliveries from an electronic medical record-based cohort (n = 223,512) conducted in 11 US states and the District of Columbia from 2002 to 2008. Increasing income inequality was defined as a positive change in state-level Gini coefficient from the year prior to birth. Multi-level models estimated the independent effect of increasing inequality on preterm birth (>22 and <37 weeks) controlling for maternal demographics, health behaviors, insurance status, chronic medical conditions, and state-level poverty and unemployment during the year of birth. Results The preterm birth rate was 12.3 % where inequality increased and 10.9 % where it did not. After adjustment, increasing inequality remained significantly associated with preterm birth (adjusted odds ratio 1.07, 95 % confidence interval 1.04, 1.11). We observed no significant interaction by insurance status or race, suggesting that increasing inequality had a broad effect across the population. Conclusions The contextual effect of increasing income inequality on preterm birth risk merits further study.

show abstract

Section: Discussionmentioning

confidence: 74%

Preterm Birth in the Context of Increasing Income Inequality

Wallace

Mendola

Chen

et al. 2015

Matern Child Health J

View full text Add to dashboard Cite

show abstract

“…Deaths were identified using the discharge status; in-hospital death during the first year was identified by record linkage. The mortality information provided by DRGs was verified via a national standard procedure with linkage to national death registries [13–15]. …”

Section: Methodsmentioning

confidence: 99%

Prenatal and post-natal cost of small for gestational age infants: a national study

Alicia¹,

Filipović-Pierucci²,

Baud

et al. 2017

BMC Health Serv Res

View full text Add to dashboard Cite

BackgroundSmall for gestational age (SGA) infants are at increased risk for preterm birth morbidities as well as a range of adverse perinatal outcomes that result in part from associated premature birth. We sought to evaluate the costs of SGA versus appropriate for gestational age (AGA) infants in France from pregnancy through the first year of life and separate the contributions of prematurity from the contribution of foetal growth on costs.MethodsThis is a cross-sectional population-based study using national hospital discharge data from French public and private hospitals. SGA infants were defined as newborns with a birth weight below the 10th percentile of French intrauterine growth curves adjusted for foetal sex. AGA infants were defined as newborns with a birth weight between the 25th and the 75th. All births were selected between January 1st, 2011 and December 31st, 2011. Costs were calculated from the hospital perspective for both mothers and children using their diagnostic related group and the French national cost study. Hospital outcomes were extracted from the database and compared by gestational age and mode of delivery.ResultsOf 777,720 total births in 2011, 84,688 SGA births (10.9%) and 395,760 AGA births (50.8%) were identified. After adjustment for gestational age, the cost for an SGA infant was €2,783 higher than for an AGA infant. The total maternal and infant hospital cost of SGA in France was estimated at 23% the total cost for deliveries. The high cost is explained by higher complication rates, more frequent hospital readmissions and longer lengths of stay.ConclusionsBeing small for gestational age is an independent contributor to 1-year hospital costs for both mothers and infants.

show abstract

“…The economic consequences are very important as one-third of expenses due to neonatal care and one-tenth of expenses due to general pediatric care are caused by premature births. As an example, the neonatal care costs of an infant with a birth weight of 500–700 g in the USA is estimated at approximately USD $225,000 [10,11]. …”

Section: Obstetrical Antibiotic Indications During Pregnancymentioning

confidence: 99%

Antibiotic Use and Misuse during Pregnancy and Delivery: Benefits and Risks

Tejada

2014

IJERPH

View full text Add to dashboard Cite

Although pregnancy is considered as a physiological state, most pregnant women in developed countries receive multiple medications to prevent maternal or neonatal complications, with antibiotics among the most frequently prescribed. During pregnancy, antibiotics are often prescribed in the context of preterm labor, intrapartum fever, prevention of neonatal Group B Streptococcus fever, and cesarean section. Outside this period, they are commonly prescribed in the community setting for respiratory, urinary, and ear, nose and throat infection symptoms. Whereas some of the current indications have insightful reasons to justify their use, potential risks related to overuse and misuse may surpass the benefits. Of note, the recent 2014 World Health Assembly expressed serious concern regarding antibiotic resistance due to antibiotic overuse and misuse and urged immediate action to combat antibiotic resistance on a global scale. Most studies in the obstetrics field have focused on the benefits of antibiotics for short-term maternal and neonatal complications, but with very little (if any) interest in long-term consequences.

show abstract

Economic analysis of the costs associated with prematurity from a literature review

Cited by 47 publications

References 34 publications

Preterm Birth in the Context of Increasing Income Inequality

Preterm Birth in the Context of Increasing Income Inequality

Prenatal and post-natal cost of small for gestational age infants: a national study

Antibiotic Use and Misuse during Pregnancy and Delivery: Benefits and Risks

Contact Info

Product

Resources

About