Ecology of house dust mites in Oxfordshire

Hart, Barbara; Whitehead, Lynne

doi:10.1111/j.1365-2222.1990.tb02669.x

Cited by 79 publications

(82 citation statements)

References 21 publications

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“…This species has a higher abundance in beds relative to carpets than Dermatophagoides, which may increase human exposure [1]. It has been directly shown by van Hage–Hamsten et al [28] that E. maynei produces IgE–binding specificities distinct from Dermatophagoides and can be a common cause of sensitization.…”

Section: Discussionmentioning

confidence: 99%

“…Euroglyphus maynei has a wide geographical distribution [1, 2, 3, 4]. Although Dermatophagoides pteronyssinus and Dermatophagoides farinae are usually the most prevalent species of house dust mite, in some houses up to 80% are E. maynei [3] occurring as mixed populations with either D. pteronyssinus [3], D. farinae [4, 5] or Blomia tropicalis [6].…”

Section: Introductionmentioning

confidence: 99%

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Molecular Analysis of the Group 1 and 2 Allergens from the House Dust Mite, Euroglyphus maynei

Smith

Mills

Hazell

et al. 1999

Int Arch Allergy Immunol

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Background: There is increasing evidence that the house dust mite Euroglyphus maynei may be a significant source of allergic sensitization. The structural information for the E. maynei allergens is largely restricted to a single partial genomic sequence of Eur m 1. Methods: A cDNA library was constructed from a culture of E. maynei. Clones encoding the major group 1 and 2 allergens were isolated by DNA hybridization and sequenced. Results: The sequence of several full length clones of Eur m 1 and Eur m 2 were obtained. The full pre–proenzyme sequence of the cysteine protease Eur m 1 was determined. The translated amino acid sequence of Eur m 1 and Eur m 2 had 84–86% sequence identity with the corresponding allergens from Dermatophagoides pteronyssinus and Dermatophagoides farinae mites. This is the same as the degree of sequence identity found between D. pteronyssinus and D. farinae despite Euroglyphus being a member of the Pyroglyphinae subfamily rather than the Dermatophagoidinae subfamily. Conclusion: The sequences of the major Eur m 1 and Eur m 2 allergens are described. Their degree of divergence from the Dermatophagoides spp. is similar to that observed between D. pteronyssinus and D. farinae group 1 and group 2 allergens.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Molecular Analysis of the Group 1 and 2 Allergens from the House Dust Mite, Euroglyphus maynei

Smith

Mills

Hazell

et al. 1999

Int Arch Allergy Immunol

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“…This may be true in moderate and humid climates where dampness and mold are present in the same apartments (67,68). However in colder subarctic climates such as Scandinavia, the conditions are dif-ferent during the heating season.…”

Section: Allergic Diseasesmentioning

confidence: 99%

Health effects of indoor-air microorganisms

Husman¹

1996

Scand J Work Environ Health

236

156

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“…House dust mites (HDM) of the family Pyroglyphidae are amongst the most important sources of indoor allergens [1, 2]. HDM allergens are widely distributed in modern homes, especially in bedding [3].…”

Section: Introductionmentioning

confidence: 99%

Encasement of Bedding Does Not Improve Asthma in Atopic Adult Asthmatics

Dharmage

Walters

Thien

et al. 2006

Int Arch Allergy Immunol

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Aim: We evaluated the impact of impermeable bed covers on asthma in asthmatics with clinically relevant house dust mite (HDM) sensitization. Methods: The study included 32 HDM-sensitized asthmatics in whom HDM allergy was considered as a significant factor in their asthma. They were randomized into either an intervention group whose bedding was encased with impermeable covers, or a control group who received cotton covers. Before and 3 and 6 months after encasement, dust samples were collected from the bedding and assayed for Der p 1. Clinical outcomes included quality of life, lung function, bronchial reactivity to methacholine, symptoms, medications and peak flow rates. Results: Baseline Der p 1 levels in both the active and the placebo groups were comparable and high (19.2 vs 18.9 µg/g of dust). There was a significant reduction in Der p 1 levels in the active group after 6 months, but not in the placebo group (7.3 vs 21.9 µg/g of dust). Quality of life improved significantly in both the intervention and control groups, but there was no significant difference in the improvements between the groups. There was no significant change in lung function, symptoms, and requirements for medications. Conclusions: Encasement of bedding significantly reduced the Der p 1 levels. However, this was not sufficient to produce worthwhile clinical improvement in those in whom dust mite avoidance might well have been recommended as part of their clinical management.

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Ecology of house dust mites in Oxfordshire

Cited by 79 publications

References 21 publications

Molecular Analysis of the Group 1 and 2 Allergens from the House Dust Mite, Euroglyphus maynei

Molecular Analysis of the Group 1 and 2 Allergens from the House Dust Mite, Euroglyphus maynei

Health effects of indoor-air microorganisms

Encasement of Bedding Does Not Improve Asthma in Atopic Adult Asthmatics

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