Ecological risk of anthropogenic pollutants to reptiles: Evaluating assumptions of sensitivity and exposure

Weir, Scott M.; Suski, Jamie G.; Salice, Christopher J.

doi:10.1016/j.envpol.2010.08.011

Cited by 90 publications

(56 citation statements)

References 55 publications

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“…Because of relatively simple monooxygenases enzyme systems [31] and low metabolic rates of lizards [32], they may not be able to detoxify pesticides at the same high rates as warmblooded birds or mammals. Therefore, risk estimates used surrogate species were convenient, but risk estimates based on bird were not rational [33].…”

Section: Neurological Effectsmentioning

confidence: 99%

Distribution, Metabolism and Toxic Effects of Beta-Cypermethrin in Lizards ( Eremias argus ) Following Oral Administration

Chen

Diao

et al. 2016

Journal of Hazardous Materials

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Section: Neurological Effectsmentioning

confidence: 99%

Distribution, Metabolism and Toxic Effects of Beta-Cypermethrin in Lizards ( Eremias argus ) Following Oral Administration

Chen

Diao

et al. 2016

Journal of Hazardous Materials

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“…Past attention was focused on measuring body burdens of various pollutants to wild reptiles which gave an understanding of historical exposure of given populations (Buono et al, 2007;Holem et al, 2008;Mann et al, 2007;Moss et al, 2009;Trinchella et al, 2006;De Falco et al, 2007;Keller et al, 2006;Simoniello et al, 2010;van de Merwe et al, 2010). However, the population-level effects and actual risks of pollutants on reptiles are still generally understudied (Weir et al, 2010). In soil, TF is easily decomposed and converted to TN with a halflife of 6-30 days (Petrovic et al, 1993;Singh, 2005).…”

Section: Introductionmentioning

confidence: 99%

Stereoselective metabolism, distribution, and bioaccumulation brof triadimefon and triadimenol in lizards

Wang

et al. 2014

Ecotoxicology and Environmental Safety

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a b s t r a c tIn this research, Chinese lizards (Eremias argus) were chosen as laboratory animal to evaluate the stereoselectivity in the processes of metabolism, distribution, and bioaccumulation of triadimefon. A validated chiral high-performance liquid chromatography coupled with triple quadruple mass spectrometry (HPLC-MS/MS) method was developed for determining enantiomers' residues of parent compound triadimefon and its metabolite triadimenol in lizard blood and tissues. Pharmacokinetic results of single-does exposure suggested that S-(þ )-triadimefon was metabolized easier than R-( À )-triadimefon, and RR-(þ )-triadimenol was the main metabolic product of triadimefon. During the continuous exposure of two dose (40 mg/kg bw Á d and 200 mg/kg bw Á d), enantiomers of triadimefon and triadimenol were detected in all body compartments, with the highest triadimefon concentrations in brain. However, the triadimenol concentrations were not significantly different among the compartments. The concentrations of RS-( þ)-triadimenol were negative correlated with concentrations of RR-(þ )-triadimenol both in blood (r¼ À0.775, p¼0.024) and liver (r¼ À0.834, p¼0.02) in 200 mg/kg bw Á d group, which indicates that chiral conversion between enantiomers of triadimenol might exist in the metabolic process of triadimefon. In all the processes, the enantiomer fractions (EFs) of R-(À )-triadimefon and RR-(þ )-triadimenol were significantly different from their natural ratios, 0.5 and 0.1, respectively, which proved that metabolism, bioaccumulation, and distribution of triadimefon and triadimenol in lizards were enantioselective. These results help enrich and supplement the knowledge of the stereoselective behaviour of triadimefon and triadimenol in reptile.

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“…Remarkably few studies on PCB exposure and effects on wild turtles have been conducted (Weir et al 2010, Salice et al 2014. Dose-response studies provide an avenue of inquiry and indicate that PCBs can cause adverse impacts to individual turtles (e.g.…”

Section: Introductionmentioning

confidence: 99%

Population status of freshwater turtles across a PCB contamination gradient

Gibbs¹,

Rouhani²,

Shams³

2017

Aquat. Biol.

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Remarkably few studies on the effects of PCBs on wild turtles have been conducted. We contrasted population-level parameters of 2 species of freshwater turtles, the snapping turtle Chelydra serpentina and the painted turtle Chrysemys picta, across a strong PCB concentration gradient in the upper Hudson River, New York State, USA. Our study employed standardized capture methods that yielded 465 turtles during 1968 trap-nights over 2 yr (2006 and 2007) at 246 trapping sites. Individuals of both turtle species were relatively heavier in a contaminated river segment, but PCB concentration did not otherwise influence relative abundance of turtles, probabilities of habitat occupancy or detection, sex or age ratios, body size, incidence of deformities, external parasite occurrence, or several movement parameters in a manner consistent with adverse impacts to wild turtles. This lack of spatial trend in parameters of wild populations of aquatic turtles across a strong gradient of PCB contamination contrasts with predictions of adverse impacts derived from population modeling, dose-response studies, and tissue residue analyses.

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Ecological risk of anthropogenic pollutants to reptiles: Evaluating assumptions of sensitivity and exposure

Cited by 90 publications

References 55 publications

Distribution, Metabolism and Toxic Effects of Beta-Cypermethrin in Lizards ( Eremias argus ) Following Oral Administration

Distribution, Metabolism and Toxic Effects of Beta-Cypermethrin in Lizards ( Eremias argus ) Following Oral Administration

Stereoselective metabolism, distribution, and bioaccumulation brof triadimefon and triadimenol in lizards

Population status of freshwater turtles across a PCB contamination gradient

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