“…Genome-wide analyses in yeast have been successfully used to identify the genes responsible for yeast response and resistance to environmental stress, in particular those induced by xenobiotic compounds of agricultural interest, such as the herbicide sulfometuron methyl (Jia et al, 2000), the dithiocarbamate fungicides mancozeb (Dias et al, 2010;Santos et al, 2009), thiuram, zineb and maneb (Kitagawa et al, 2003), the benzimidazole fungicide benomyl (Lucau-Danila et al, 2005), the pesticide lindane (Parveen et al, 2003), and the herbicide 2,4-D Teixeira et al, 2006;. Even though many cytotoxic compounds used in agriculture may act in their target organisms via physiological mechanisms that do not exist in yeast, many of the basic mechanisms underlying resistance and adaptation to chemical and environmental stresses are apparently conserved among phylogenetically distant organisms (Landis & Yu, 1999).…”