Ecofriendly Synthesis of Silver–Carboxy Methyl Cellulose Nanocomposites and Their Antibacterial Activity

Li, Gang; Liu, Luqing; Yu, Sun; Liu, Huihong

doi:10.1007/s10876-018-1426-y

Cited by 23 publications

(6 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This augmented antibacterial activity found might be on account of the Ag-O coordination bonds among AgNPs and COO − moieties of CMC, increasing the ability of AgNPs to release Ag + ions into the aqueous dispersion. 59 In the same way as AgNPs, the exact mechanism for slight antibacterial activity of CMC has not been reported in previous studies. However, similar to chitosan, it is suggested that CMC might react with both the bacterial cell wall and the cell membrane, since it also have hydroxyl groups of the glucopyranose monomers.…”

Section: Resultsmentioning

confidence: 92%

“… 45 Li et al and Hassabo et al also reported SPR bands at closer wavelengths ie, 404 nm and 413 nm, respectively, in spectrums of CMC-based AgNPs. 59 , 60 The facial appearance, surface morphology, and internal structure of the synthesized CMC-AgNPs were demonstrated by scanning and transmission electron microscopy. Agglomeration and spherical shape AgNPs were observed in SEM images.…”

Section: Resultsmentioning

confidence: 99%

“…Similar monodispersion with nearer particle size range was observed by Li et al in CMC containing AgNPs. 59 Figure 7 shows the typical pore size distribution of synthesized nanocomposite. From the graph, we can observe that most of the micropores of CMC-AgNPs with a size smaller than 50 nm, the mean pore size from the peak position is about 18.2 nm, and possesses a relatively narrow pore size distribution.…”

Section: Resultsmentioning

confidence: 99%

“…Similar augmented antibacterial activity of CMC based AgNPs was also reported in previous studies. 59 , 60 The exact mechanism for growth inhibition of bacterial strains by AgNPs is still not identified, while several researchers have reported the plausible bacterial killing mechanism by AgNPs. It has been suggested that the high affinity of AgNPs with the surface-active groups of bacterial strains has produced more significant bactericidal effects.…”

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Green Synthesis and Characterization of Carboxymethyl Cellulose Fabricated Silver-Based Nanocomposite for Various Therapeutic Applications

Asghar

Yousuf

Shoaib

et al. 2021

IJN

View full text Add to dashboard Cite

Purpose The current study proposed the simple, eco-friendly and cost-effective synthesis of carboxymethyl cellulose (CMC) structured silver-based nanocomposite (CMC-AgNPs) using Syzygium aromaticum buds extract. Methods The CMC-AgNPs were characterized by ultraviolet (UV) spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier transmission infra-red (FTIR), energy-dispersive X-ray (EDX), and dynamic light scattering (DLS) techniques. The synthesized nanocomposites were evaluated for their bactericidal kinetics, in-vivo anti-inflammatory, anti-leishmaniasis, antioxidant and cytotoxic activities using different in-vitro and in-vivo models. Results The spherical shape nanocomposite of CMC-AgNPs was synthesized with the mean size range of 20–30 nm, and the average pore diameter is 18.2 nm while the mean zeta potential of −31.6 ± 3.64 mV. The highly significant (P < 0.005) antibacterial activity was found against six bacterial strains with the ZIs of 24.6 to 27.9 mm. More drop counts were observed in Gram-negative strains after 10 min exposure with CMC-AgNPs. Significant damage in bacterial cell membrane was also observed in atomic force microscopy (AFM) after treated with CMC-AgNPs. Nanocomposite showed highly significant anti-inflammatory activity in cotton pellet induced granuloma model (Phase I) in rats with the mean inhibitions of 43.13% and 48.68% at the doses of 0.025 and 0.05 mg/kg, respectively, when compared to control. Reduction in rat paw edema (Phase II) was also highly significant (0.025 mg/kg; 42.39%; 0.05 mg/kg, 47.82%). At dose of 0.05 mg/kg, CMC-AgNPs caused highly significant decrease in leukocyte counts (922 ± 83), levels of CRP (8.4 ± 0.73 mg/mL), IL-1 (177.4 ± 21.3 pg/mL), IL-2 (83.7 ± 11.5 pg/mL), IL-6 (83.7 ± 11.5 pg/mL) and TNF-α (18.3 ± 5.3 pg/mL) as compared to control group. CMC-AgNPs produced highly effective anti-leishmaniasis activity with the viable Leishmania major counts decreased up to 36.7% within 24 h, and the IC 50 was found to be 28.41 μg/mL. The potent DPPH radical scavenging potential was also observed for CMC-AgNPs with the IC 50 value of 112 μg/mL. Furthermore, the cytotoxicity was assessed using HeLa cell lines with the LC 50 of 108.2 μg/mL. Conclusion The current findings demonstrate positive attributes of CMC fabricated AgNPs as a promising antibacterial, anti-inflammatory, anti-leishmaniasis, and antioxidant agent with low cytotoxic potential.

show abstract

Section: Resultsmentioning

confidence: 92%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Green Synthesis and Characterization of Carboxymethyl Cellulose Fabricated Silver-Based Nanocomposite for Various Therapeutic Applications

Asghar

Yousuf

Shoaib

et al. 2021

IJN

View full text Add to dashboard Cite

show abstract

“…Los esfuerzos por disminuir el impacto ambiental de estas técnicas han llevado al desarrollo de vías de síntesis alternativas que hacen uso de sistemas biológicos [Wan Mat Khalir et al, 2020;Zhao et al, 2018]. El uso de carbohidratos y polisacáridos para obtener AgNPs coloidales ha sido explotado debido a la capacidad estabilizante de estos compuestos, entre ellos, los más utilizados son el alginato, el quitosano y la carboximetilcelulosa [Shervani & Yamamoto, 2011;Thangaraj et al, 2017;Hasan et al, 2020;Li et al, 2018]. En estos casos se ha reportado la obtención de sistemas de AgNPs bien dispersos, estables, cristalinos, y los carbohidratos empleados han actuado también como agentes reductores.…”

Section: Capítulo I: Introducción General 24unclassified

Obtención de arreglos regulares metálicos sobre superficies de sistemas nanopartícula-proteína y su aplicación en catálisis

Huggias

Peruzzo

Bolla

View full text Add to dashboard Cite

El diseño y preparación de arreglos regulares de nanopartículas metálicas tienen gran relevancia en la actualidad ya que han demostrado tener propiedades catalíticas excepcionales. Uno de los mayores desafíos en este campo es desarrollar métodos que permitan obtener estos ensamblados en nanoescala perfectamente dirigidos y controlados. Desde la bionanotecnología se han introducido grandes aportes, entre los que se destaca el empleo de proteínas en estrategias de construcción biomolecular. En este sentido, las proteínas de capa-S han emergido como bloques de construcción de arreglos de nanopartículas metálicas al combinar la capacidad para autoensamblarse formando arreglos nanométricos sobre distintas superficies, a su habilidad para sintetizar nanopartículas metálicas. No obstante, aún quedan muchos aspectos por explorar sobre estas proteínas con el fin de desarrollar nuevos productos tecnológicos basados en nanopartículas metálicas para su aplicación en catálisis. Por esto, el presente trabajo de tesis propone el diseño de un sistema compuesto por proteínas de capa-S y partículas poliméricas para su posterior empleo en la síntesis de nanopartículas metálicas con la finalidad de obtener un bionanocatalizador activo frente a reacciones de hidrogenación en fase acuosa. El mismo inicia con la síntesis de cuatro dispersiones acuosas de partículas poliméricas, diseñadas con el propósito de ofrecer a las proteínas de capa-S una variedad de superficies sobre las que adsorberse. Las dispersiones obtenidas resultaron ser coloidalmente estables, con partículas de tamaño similar y con densidad de carga superficial negativa asociada a la presencia de grupos oxhidrilos, sulfatos y/o carboxilatos. Por otra parte, se realizó la extracción y purificación de dos proteínas de capa-S de dos cepas de Lactobacillus kefiri. Las proteínas de capa-S fueron caracterizadas fisicoquímicamente en término de su composición, peso molecular, punto isoeléctrico, estructura secundaria y geometría bidimensional. Se estudió la adsorción de las proteínas sobre las partículas poliméricas realizando isotermas de adsorción que fueron modeladas según el modelo de Langmuir-Freundlich. Los sistemas resultantes fueron caracterizados fisicoquímicamente y morfológicamente evidenciándose una morfología “core-shell”. Empleando sistemas los polímero/proteína seleccionados, se lograron obtener nanopartículas de metales nobles (Pt o Ag) soportadas. El conjunto (polímero/proteína-nanopartícula metálica) presentó una morfología "strawberry", observándose nanopartículas metálicas de entre 2 y 20 nm estabilizadas sobre los soportes polímero/proteína. Los bionanocatalizadores obtenidos fueron evaluados frente a la reacción de reducción de p-nitrofenol. La performance catalítica observada fue excelente, con conversiones del orden del 95% y tiempos que variaron según la concentración del catalizador empleado en condiciones suaves de reacción. A su vez, los mismos pudieron reutilizarse en hasta 10 ciclos de uso con una disminución leve a moderada de su actividad catalítica. Estos no presentaron alteraciones fisicoquímicas importantes post-reacción. De esta manera, se logró diseñar y obtener bionanocatalizadores con excelente desempeño catalítico formados por nanopartículas de metales nobles sintetizadas (dirigidas, estabilizadas) y soportadas sobre sistemas partícula polimérica/proteína de capa-S.

show abstract

Fabrication and stabilization of green nanosilver using gardenia yellow natural dyes for efficient degradation of bacteria

Jiang

Guo

Zhang

et al. 2022

Env Prog and Sustain Energy

Self Cite

View full text Add to dashboard Cite

The various applications of silver nanoparticles (AgNPs) are brutally hampered in the practical field due to their instability and aggregation features. Thus, highly stable colloidal AgNPs were produced in obedience to the principle of 'green chemistry' that uses natural dyes extracted from gardenia fruits as stabilizing and simultaneously as reducing agents. The effect of operating conditions on the synthesis of AgNPs was studied using a one-variable-at-a-time technique to maximize the growth of particles.The analysis of AgNPs produced at optimum reaction parameters discovered that the particles are face-centered cubic metallic silver, mostly in spherical shapes, nanoranged in diameter (23.4 ± 6.4 nm) with a confined size distribution, enormously crystalline surface (d-spacing = 0.233 nm), firmly stabilized (zeta potential = À29.0 mV) by a thin membrane of gardenia phytochemicals. They exhibited significant bacterial reduction inhibition against the growth of Escherichia coli and Staphylococcus aureus owing to the strong antibacterial function of nanosilver.

show abstract

Ecofriendly Synthesis of Silver–Carboxy Methyl Cellulose Nanocomposites and Their Antibacterial Activity

Cited by 23 publications

References 28 publications

Green Synthesis and Characterization of Carboxymethyl Cellulose Fabricated Silver-Based Nanocomposite for Various Therapeutic Applications

Green Synthesis and Characterization of Carboxymethyl Cellulose Fabricated Silver-Based Nanocomposite for Various Therapeutic Applications

Obtención de arreglos regulares metálicos sobre superficies de sistemas nanopartícula-proteína y su aplicación en catálisis

Fabrication and stabilization of green nanosilver using gardenia yellow natural dyes for efficient degradation of bacteria

Contact Info

Product

Resources

About