Ecofriendly multifunctional thiolated carboxymethyl chitosan-based 3D scaffolds with luminescent properties for skin repair and theragnostic of tissue regeneration

Borsagli, Fernanda Guerra Lima Medeiros; Souza, Ana Júlia M.; Paiva, Aislan Esmeraldo

doi:10.1016/j.ijbiomac.2020.10.186

Cited by 15 publications

(3 citation statements)

References 28 publications

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“…Spectroscopic evaluation indicated the formation of disulfide bonds, confirming the mechanical stability. The findings demonstrated the thiol group incorporation, resulting in the enhanced fluorescence behavior of carboxymethyl chitosan with an excellent cytocompatibility profile . Carboxymethyl chitosan- and gelatin-based scaffolds are applicable to dermal tissue engineering.…”

Section: Biomedical Applications Of Modified Chitosanmentioning

confidence: 90%

“…The findings demonstrated the thiol group incorporation, resulting in the enhanced fluorescence behavior of carboxymethyl chitosan with an excellent cytocompatibility profile. 227 Carboxymethyl chitosan-and gelatin-based scaffolds are applicable to dermal tissue engineering. They promote angiogenesis, bioadhesion, and the proliferation of fibroblasts.…”

Section: Antimicrobial Applicationsmentioning

confidence: 99%

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Chitosan Derivatives as Carriers for Drug Delivery and Biomedical Applications

Manna

Seth

Gupta

et al. 2023

ACS Biomater. Sci. Eng.

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Over the past few decades, chitosan (CS) has gained the attention of researchers investigating newer biomaterial-based carriers for drugs in pharmaceutical and biomedical research. Combined with its nontoxic behavior, biodegradability, and biocompatibility, chitosan has found widespread applications in the fields of drug delivery, tissue engineering, and cosmetics. As a novel drug carrier, chitosan is regarded as one of the promising biomaterials in the pharmaceutical industry. The extensive use of this cationic biopolysaccharide in the delivery of therapeutic agents has brought a few limitations of chitosan into the limelight. Various chemical modifications of chitosan can minimize these limitations and improve the efficacy of chitosan as a drug carrier. The effectiveness of several chemically modified chitosan derivatives, including trimethyl chitosan, thiolated chitosan, PEGylated chitosan, and other chitosan derivatives, has been investigated by many researchers for the controlled and target specific delivery of therapeutics. The chemically modified chitosan derivatives exhibited greater importance in the current scenario on drug delivery due to their solubility in wide range of media along with their interaction with pharmaceutically active ingredients. Chitosan derivatives have also attracted attention in several biomedical fields, including wound healing, hyperthermia therapy, tissue engineering, and bioadhesives. The present review narrates the sources and common physicochemical properties of chitosan, including several important synthetic modifications to obtain chemically modified chitosans and their applications in targetspecific drug delivery, along with several biomedical applications.

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Section: Biomedical Applications Of Modified Chitosanmentioning

confidence: 90%

Section: Antimicrobial Applicationsmentioning

confidence: 99%

Chitosan Derivatives as Carriers for Drug Delivery and Biomedical Applications

Manna

Seth

Gupta

et al. 2023

ACS Biomater. Sci. Eng.

View full text Add to dashboard Cite

show abstract

“…In recent years, great efforts have been made to develop biocompatible and biodegradable devices for various applications. [1][2][3][4][5][6] With the increasing environmental awareness among the people, [7,8] more ecofriendly, [9] renewable, and biodegradable materials are being produced using cost-effective techniques. [10,11] Thus, pharmaceutical technology has focused on the development of release biodegrabable systems, [12] such as gels, that are capable of controlling the release of the drug to exactly where it is absorbed or acts at the desired rate.…”

Section: Introductionmentioning

confidence: 99%

Exploring Interactions and Properties of the Sodium Carboxymethyl Cellulose–Chitosan Biopolymer Complex

Ardhaoui,

Cherif,

Herth

2024

Physica Status Solidi (a)

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The complex of sodium carboxymethyl cellulose (CMC) and chitosan (CH) in aqueous solution can be used for biomedical applications and is very beneficial for tissue engineering, drug delivery, and disease treatment. This article presents elaboration and properties of the complex of two polysaccharides with opposite charges of CMC/CH in aqueous solutions. The electrical conductivity under the influence of increasing concentrations of the CMC/CH mixtures from (0.5 to 10) g l−1 and increasing temperatures from 288.15 to 318.15 K is investigated. The reduced conductivities, , energy of activation , the Gibbs free energy of conductivity , and the activations parameters of the enthalpy () and entropy () are estimated.

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Carboxymethyl Chitosan and Its Derivatives in Tissue Engineering

Borsagli

2023

Multifaceted Carboxymethyl Chitosan Derivatives: Properties and Biomedical Applications

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Ecofriendly multifunctional thiolated carboxymethyl chitosan-based 3D scaffolds with luminescent properties for skin repair and theragnostic of tissue regeneration

Cited by 15 publications

References 28 publications

Chitosan Derivatives as Carriers for Drug Delivery and Biomedical Applications

Chitosan Derivatives as Carriers for Drug Delivery and Biomedical Applications

Exploring Interactions and Properties of the Sodium Carboxymethyl Cellulose–Chitosan Biopolymer Complex

Carboxymethyl Chitosan and Its Derivatives in Tissue Engineering

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