Eco-friendly ultrasonic assisted liquid–liquid microextraction method based on hydrophobic deep eutectic solvent for the determination of sulfonamides in fruit juices

Recovery and Stabilization of Anthocyanins and Phenolic Antioxidants of Roselle (Hibiscus sabdariffa L.) with Hydrophilic Deep Eutectic Solvents

“…The DES (sodium acetate:formic acid) used in the present study extracted better anthocyanin from Roselle calyces. Furthermore, the application of UAE combined with DESs is well-adapted and accelerates the mass transfer of the analytes [67][68][69]. The effects of molarity ratio, additional water and solvent ratio on the response anthocyanin was well-represented by perturbation graphic generated using response surface methodology (Figure 3).…”

Deep Eutectic Solvents Application in Food Analysis

“…These hydrophobic solvents consisted of a long chain alkyl quaternary ammonium salt (e.g., tetrabutylammonium chloride (N 4444 Cl), methyltrioctylammonium chloride (N 8881 Cl), tetraheptylammonium chloride (N 7777 Cl), tetraoctylammonium chloride (N 8888 Cl), methyltrioctylammonium bromide (N 8881 Br) and tetraoctylammonium bromide (N 8888 Br)) and poorly soluble carboxylic acids (e.g., decanoic acid), and their extraction capacity was evaluated by extracting volatile fatty acids from diluted aqueous solutions. Since then, multiple HDESs based on neutral compounds have also been proposed, including combinations of monoterpenes with fatty acids [85], tetraalkylammonium halides with fatty acids and alcohols [86,87], fatty acids with fatty acids [88], and monoterpenes with monoterpenes [17]. Many of the HDESs have also been designed and classified following the same classification that had been previously proposed and that was already used for hydrophilic DESs (type I, II, III and IV), but due to their need to be stable in the aquatic environment, they are mainly grouped into type III (a combination of a quaternary salt (HBA) with a HBD) and type IV (a combination of metal chloride with HBD) [89].…”

“…Currently, studies on the synthesis and application of HDESs for the extraction of a great variety of analytes from food matrices have expanded rapidly, which has led to an increase in the number of articles published in recent years. As can be seen in Table 2, several HDESs have been used for the extraction of both organic (phthalic acid esters [18,96,99], dyes [97,104,110,117], PAHs [17,85], sterols [98], pesticides [100,105,112,122,124,126,127], herbicides [102], insecticides [125], preservatives [101], pigments [86], antibiotics [87,103,108,114], fluorescent whitening agents [106], vitamins [107], mycotoxins [16], bisphenols [115], perfluoroalkyl substances [120] and terpenes [121]) and inorganic compounds (Co, Cd, Ni, As, V and Pb [109,111,113,116,118,119,123]) from aqueous phases (water [96,113,118,124], soft drinks…”

Microextraction Techniques with Deep Eutectic Solvents

“…In addition to the application for environmental samples, there are references for food and biological samples, [112,113], such as Ji's et al research for determination of sulfonamides in fruit juices with HPLC-UV. In this experiment, 0.8 mL of a TAC and 2-octanol DES (1:2 molar ratio) was used as extraction solvent to preconcentrate sulfapyridine, sulfamethazine, and sulfamethoxine through UA-DES-LLME.…”