Eco-friendly Synthesis of Zinc Oxide Nanoparticles by Clerodendrum heterophyllum Leaf Extract and Their Biological Applications

Kirubakaran, Dharmalingam; Selvam, Kuppusamy; Lavanya, Mathiazhakan; Shivaswamy, Muthugounder Subaramanian; Sivasakthi, Vairakkannu; BaigBaig, Ameer Ali

doi:10.1007/s12668-023-01222-x

Cited by 6 publications

(2 citation statements)

References 41 publications

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“…Recent research on ZnONPs in Carica papaya tested for ABTS and DPPH showed IC 50 values of 130.1 μg/mL and 104.9 μg/mL, respectively, compared to similar data found in S. cordifolia [62] . ZnO nanomaterial‘s antioxidant defense mechanisms against free radicals and the capacity of oxygen atoms to donate electrons are note‐worthy [63,64] . The nanoparticle reduction of free radicals in the production of reactive oxygen species (ROS) triggers cellular processes such as protein synthesis, respiration, food metabolism, and DNA replication, leading to cell death [65,66] .…”

Section: Discussionmentioning

confidence: 55%

“…[62] ZnO nanomaterial's antioxidant defense mechanisms against free radicals and the capacity of oxygen atoms to donate electrons are note-worthy. [63,64] The nanoparticle reduction of free radicals in the production of reactive oxygen species (ROS) triggers cellular processes such as protein synthesis, respiration, food metabolism, and DNA replication, leading to cell death. [65,66] In our study, we investigated the relationship between AChE and BChE enzyme inhibition systems with ZnO NPs.…”

Section: In-vivo Wound Healing Activity Of Znonpsmentioning

confidence: 99%

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Bio‐fabrication of Zinc oxide nanoparticles using Strobilanthes cordifolia: Characterization and evaluation of antioxidant, anti‐cholinergic, anti‐inflammatory and wound healing activities

Kirubakaran,

Selvam,

Subramanian Shivakumar

et al. 2024

ChemistrySelect

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Strobilanthes cordifolia has emerged as a promising material in traditional medicine. In this study, we have made an attempt to synthesize zinc oxide nanoparticles derived from S. cordifolia leaf. The team employed a wide range of techniques including UV, FT‐IR, XRD, FE‐SEM with EDAX, HR‐TEM with SAED, DLS, Zeta potential, BET and PZC analysis to thoroughly examine the properties of the NPs. FTIR analysis provided evidence of various functional groups within the NPs. XRD analysis demonstrated the crystal nature and phase purity of the NPs. SEM analysis showcased the spherical shape of the particles, while TEM revealed their rod‐like shape with sizes averaging at approximately 10 nm. DLS analysis indicated the average particle size, and the high zeta potential value confirmed the stability and BET analysis deciphered the specific surface area of the biosynthesized NPs. The NPs confirmed strong antioxidant properties with DPPH, ABTS, and hydroxyl radicals. Enzyme studies confirmed good anti‐cholinergic activity and anti‐inflammatory efficacy, highlighting their potential therapeutic benefits. The NPs demonstrated promising wound healing properties. Overall, this research study sheds light on the medicinal aspects of zinc oxide nanoparticles from S. cordifolia leaf extract and it offers exciting prospects for future exploration and development in this field.

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Section: Discussionmentioning

confidence: 55%