Eco-Friendly Cloud Point Extraction Coupled With a Spectrophotometric Method for the Determination of Ranitidine Hydrochloride in Pharmaceutical Samples
Abstract:The simple, rapid, economical, and environmentally friendly method was developed for spectrophotometric determination of ranitidine hydrochloride (R-HCl) in pharmaceutical samples after extraction by the cloud point method. The method based on the reduction of Fe(III) by ranitidine hydrochloride to Fe(II), which subsequently reacted with ferricyanide to form colored products at (pH 4.0), then Triton X–114 surfactant was used as an extractant for ranitidine hydrochloride. The linearity of the calibration curve … Show more
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