Eco‐Efficient Synthesis of New Pyrido [2, 3‐c] Coumarin Scaffolds Under Sonochemical Method

Chidurala, Praveen; Jetti, Venkateshwarlu; Pagadala, Ramakanth; Meshram, Jyotsna S.; Jonnalagadda, Sreekantha B.

doi:10.1002/jhet.2319

Cited by 10 publications

(2 citation statements)

References 63 publications

(19 reference statements)

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“…Another successful example for the synthesis of 2 H ‐pyridine fused coumarin of type 80 via a four‐component treatment of 4‐hydroxycoumarin 1 , aldehyde 31 , acetoacetanilide 79 , and ammonium acetate 34 were established by Chidurala and his group (Scheme 27). [83] By using ethanol as the solvent, they synthesized the corresponding 2 H ‐pyridines products 80 via conventional as well as ultrasound irradiation methods. With the conventional method, the products 80 were achieved in 45–72% yield, whereas under the influence of ultrasound irradiation the products 80 were obtained in 75–90% yield within a very short reaction time.…”

Section: Synthesis Of Six‐membered Heterocycles Via Metal‐free Multic...mentioning

confidence: 99%

4‐Hydroxycoumarin: A Versatile Substrate for Transition‐metal‐free Multicomponent Synthesis of Bioactive Heterocycles

2021

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One-pot multi-component reactions especially under transition-metal-free catalysis served as an efficient, and environmentally friendly method for the construction of value-added compounds. Their importance in organic synthesis has drastically increased due to their operational simplicity, cost-effectiveness, step-and pot-economic nature. On the other hand, the molecular hybridization concept has recently emerged as a key fascinating area in medicinal and organic chemistry for the design of new drugs. Owing to the widespread occurrence in natural products, and pharmaceutical agents, the incorporation of another heterocycle either as substituents or as a fused material into 4-hydroxycoumarin moiety offers new opportunities for the broad application of the targeted coumarin-heterocycles into many branches of chemistry. Considering the importance of both the topics, here we have reviewed the developments achieved in the synthesis of diverse medicinally privileged oxygen, and nitrogen-containing heterocycles as well as spiro-heterocycles either linked or fused with coumarin moiety by using readily accessible 4-hydroxycoumarin as the starting material via one-pot multi-component reaction under transition-metalfree conditions.[a] B. Borah, K.

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Section: Synthesis Of Six‐membered Heterocycles Via Metal‐free Multic...mentioning

confidence: 99%

4‐Hydroxycoumarin: A Versatile Substrate for Transition‐metal‐free Multicomponent Synthesis of Bioactive Heterocycles

2021

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“…Eco‐efficient synthesis of new pyrido [2, 3‐ c ] coumarin scaffolds 80 under sonochemical method has been developed by Praveen Chidurala et al . (Scheme ).…”

Section: Synthesis Of Pyridocoumarinsmentioning

confidence: 99%

A Concise Review on Pyridocoumarin/Azacoumarin Derivatives: Synthesis and Biological Activity

Patra¹

2019

ChemistrySelect

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Coumarins are important due to their versatile bio‐activity. Synthesised pyridocoumarin derivatives show remarkable biological activities including antifungal, antibacterial, antitumor, antiHIV, and antimicrobial activity. The present review aims to review a vast body of literature on different synthetic methodology mainly aza‐Diels Alder reaction, metal catalyzed cyclization and multicomponent reaction and bioactivity of pyridocoumarin derivatives as published during the period from 1997 up to 2017. The synthesised compounds have been reported in literature either by construction of pyridine, pyran or of both ring starting from suitable precursors.

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ChemInform Abstract: Eco‐Efficient Synthesis of New Pyrido[2,3‐c] Coumarin Scaffolds under Sonochemical Method.

et al. 2016

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Eco‐Efficient Synthesis of New Pyrido [2, 3‐c] Coumarin Scaffolds Under Sonochemical Method

Cited by 10 publications

References 63 publications

4‐Hydroxycoumarin: A Versatile Substrate for Transition‐metal‐free Multicomponent Synthesis of Bioactive Heterocycles

4‐Hydroxycoumarin: A Versatile Substrate for Transition‐metal‐free Multicomponent Synthesis of Bioactive Heterocycles

A Concise Review on Pyridocoumarin/Azacoumarin Derivatives: Synthesis and Biological Activity

ChemInform Abstract: Eco‐Efficient Synthesis of New Pyrido[2,3‐c] Coumarin Scaffolds under Sonochemical Method.

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