Echographic Examinations on 110 Histologically Proven Intraocular Melanomas

Rochels, R.; Nover, A; Neumann, T; Adam, Fadoul

doi:10.1007/978-3-662-02371-6_21

Cited by 3 publications

(7 citation statements)

References 2 publications

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“…This percentage is almost double compared to Coleman's [4] finding. Several authors even stated to have found a still higher percentage than 75% [14,15]. A possible explanation was given by Poujol et al [13].…”

Section: Discussionmentioning

confidence: 87%

“…In the literature the terms 'replacement of the choroid' [3,4,6] and 'choroidal infiltration' [15,18] are mentioned as histological references of choroidal excavation. Choroidal infiltration means penetration into the choroid by the tumour.…”

Section: Discussionmentioning

confidence: 99%

“…Reflectivity (Table 1) The acoustic hallmark of melanomas is their low to medium reflectivity, which is the result of a compact cellular structure with minimal intercellular structure [15]. Five subgroups were made: (1) Low reflectivity (36%), (2) Low to medium reflectivity (32%), (3) Medium reflectivity (32%), (4) Medium to high reflectivity (0%), (5) High reflectivity (0%).…”

Section: Vascularisation Of the Tumourmentioning

confidence: 99%

“…Echography has proved to be effective in the differential diagnosis of malignant melanoma of the choroid, also in eyes with opaque media not accessible for other diagnostic techniques [11,14,18]. By employing echography, several authors have reported to obtain very high accuracy rates in differentiating choroidal melanomas from other choroidal lesions such as choroidal hemangioma, choroidal metastasis as well as melanoma mimicking lesions [3,6,8,9,11,15,18]. Evaluation of the literature on choroidal tumours submitted to Bscan echography has resulted in the notion that certain specific characteristics are useful in differentiating choroidal lesions [1-4, 6, 7, 11, 14, 15, 18].…”

Section: Introductionmentioning

confidence: 99%

“…Only few references to histological findings have been published. Nevertheless, choroidal infiltration [15,18] and replacement of the choroid [3,4,6] have been reported. Coleman [4] observed the phenomenon of choroidal excavation in about 40% of choroidal melanomas and not in other kinds of choroidal tumours.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

B-mode echography of choroidal melanoma; echographic and histological aspects of choroidal excavation

Gool¹,

Thijssen²,

Verbeek³

1991

Int Ophthalmol

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The B-mode images of 32 patients affected with a malignant melanoma of the choroid were studied, in particular with respect to choroidal excavation. The degree of visibility of choroidal excavation at the B-scan was compared with the thickness of the choroid, scleral invasion, vascularisation, retinal detachment and the reflectivity of the tumour. None of these histological and echographical features appeared to be significantly related to the degree of the visibility of choroidal excavation. Also the condition of the choroid was studied. At examination of all the histological sections no choroid was found between tumour and sclera. This implies that choroidal excavation should be visible at echograms in every case instead of only in 75% of the cases as was found for our series.

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Section: Discussionmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Section: Vascularisation Of the Tumourmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

B-mode echography of choroidal melanoma; echographic and histological aspects of choroidal excavation

Gool¹,

Thijssen²,

Verbeek³

1991

Int Ophthalmol

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Erkrankungen des Augapfels aus echographischer Sicht

Trier¹,

Haigis²,

Fledelius³

et al. 1989

Ophthalmologische Ultraschalldiagnostik

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Echographic differentation of intraocular melanomas by computer analysis

Thijssen

Verbeek

Romijn

et al. 1992

Acta Ophthalmologica

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The aim of this study was to assess the d a erentiation of histologically different types of choroidal melanomas by means of clinical and quantitative acoustic/texture parameters of echograms. Clinical parameters were graded by morphological, kinetic and quantitative statements about the A-and B-mode echograms by a skilled diagnostician. Acoustic/texture parameters were obtained by processing and analysing radio frequency, AM-demodulated and FM-demodulated echograms. The latter data were preprocessed to remove influence induced by beam diffraction and focusing. The best set of four clinical echographic parameters enabled a retrospective classification of spindle type melanomas vs. mixed + epithelioid type melanomas with an accuracy of 77% (area under the ROC-curve of 86%). The discriminant analysis performed with the best four acoustic/texture parameters (n = 30) yielded a sensitivity of 89%, a specificity of 92%, and an area under the ROC-curve which corresponds to a probability of correct classification of 96.6%. When using these data prospectively to classify tumours of unknown cell type (n = 21), this classification could be performed in 86% of cases.

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Echographic Examinations on 110 Histologically Proven Intraocular Melanomas

Cited by 3 publications

References 2 publications

B-mode echography of choroidal melanoma; echographic and histological aspects of choroidal excavation

B-mode echography of choroidal melanoma; echographic and histological aspects of choroidal excavation

Erkrankungen des Augapfels aus echographischer Sicht

Echographic differentation of intraocular melanomas by computer analysis

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