Echoendoscopic appearance of mediastinal metastasis from papillary renal carcinoma

Piro, Roberto; Tonelli, Roberto; Cavazza, Alberto; Taddei, Sofia; Clini, Enrico; Facciolongo, Nicola

doi:10.1111/1759-7714.13704

Cited by 1 publication

(2 citation statements)

References 5 publications

(7 reference statements)

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“…EBUS is currently widely used in the diagnosis of mediastinal and hilar space-occupying lesions, which can provide the diagnostic basis for unexplained mediastinal or hilar lesions. 8 Confocal laser endomicroscopy (CLE) is another new imaging technique based on the imaging principle of the laser scanning confocal microscope. 9 It enables performing high-resolution imaging at the cellular level in vivo, which defines it as a real "optical biopsy" technology.…”

Section: Introductionmentioning

confidence: 99%

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Value of needle confocal laser microendoscopy combined with endobronchial ultrasound bronchoscopy in the diagnosis of hilar and mediastinal lymph node lesions

Zuo,

Xue,

et al. 2023

The Kaohsiung J of Med Scie

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Endobronchial ultrasound bronchoscopy (EBUS) and needle confocal laser endomicroscopy (nCLE) are techniques for screening benign and malignant lesions of the hilar and mediastinal lymph node (HMLN). This study investigated the diagnostic potential of EBUS, nCLE, and combined EBUS and nCLE in HMLN lesions. We recruited 107 patients with HMLN lesions who were examined by EBUS and nCLE. A pathological examination was performed, and the diagnostic potential of EBUS, nCLE, and combined EBUS‐nCLE approach was analyzed according to the results. Among the 107 cases of HMLN lesions, 43 cases were benign and 64 cases were malignant on pathological examination, 41 cases were benign and 66 cases were malignant on EBUS examination; 42 cases were benign and 65 cases were malignant on nCLE examination; 43 cases were benign and 64 cases were malignant on combined EBUS‐nCLE examination. The combination approach had 93.8% sensitivity, 90.7% specificity, and 0.922 area under the curve, which was higher than those of EBUS (84.4%, 72.1%, and 0.782, respectively) and nCLE diagnosis (90.6%, 83.7%, and 0.872, respectively). The combination approach had a higher positive predictive value (0.908), negative predictive value (0.881), and positive likelihood ratio (10.09) than that of EBUS (0.813, 0.721, and 3.03, respectively) and nCLE (0.892, 0.857, and 5.56, respectively), whereas, the negative likelihood ratio was lower than that for EBUS (0.22) and nCLE (0.11). No serious complications occurred in patients with HMLN lesions. To summarize, the diagnostic efficacy of nCLE was better than EBUS. The EBUS‐nCLE combination is a suitable approach for diagnosing HMLN lesions.

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Section: Introductionmentioning

confidence: 99%

“…Soon after the development of this technique, it gains attention and quickly became a new hot spot. EBUS is currently widely used in the diagnosis of mediastinal and hilar space‐occupying lesions, which can provide the diagnostic basis for unexplained mediastinal or hilar lesions 8 …”

Section: Introductionmentioning

confidence: 99%

Value of needle confocal laser microendoscopy combined with endobronchial ultrasound bronchoscopy in the diagnosis of hilar and mediastinal lymph node lesions

Zuo,

Xue,

et al. 2023

The Kaohsiung J of Med Scie

View full text Add to dashboard Cite

show abstract

Echoendoscopic appearance of mediastinal metastasis from papillary renal carcinoma

Cited by 1 publication

References 5 publications

Value of needle confocal laser microendoscopy combined with endobronchial ultrasound bronchoscopy in the diagnosis of hilar and mediastinal lymph node lesions

Value of needle confocal laser microendoscopy combined with endobronchial ultrasound bronchoscopy in the diagnosis of hilar and mediastinal lymph node lesions

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