Echocardiographic Findings in Stable Outpatients with Properly Functioning HeartMate II Left Ventricular Assist Devices

Topilsky, Yan; Oh, Jae K.; Atchison, Fawn W.; Shah, Dipesh K.; Bichara, Valentina M.; Schirger, John A.; Kushwaha, Sudhir S.; Pereira, Naveen L.; Park, Soon J.

doi:10.1016/j.echo.2010.12.022

Cited by 51 publications

(56 citation statements)

References 25 publications

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“…We next evaluated currently accepted echocardiographic and clinical values of heart failure in the CF-LVADsupported patient group both before and after LVAD implantation (Table III). Consistent with the medical literature, 18,19 the LV end-diastolic and end-systolic dimensions and estimated pulmonary artery pressures decreased by approximately 20% to 30% after LVAD implantation (P <0.001). The EPSS decreased an average of 28.5% (from 2.5 to 1.8 cm) after LVAD implantation (P <0.0001).…”

Section: Demographic Characteristics Of the Lvad Study Populationsupporting

confidence: 72%

“…Upon LVAD implantation, the E/e′ value significantly decreased from 19.4 ± 8.72 to 13.3 ± 10.91 (P=0.0042), which was similar to a published observation in hemodynamically stable outpatients. 19 The before-LVAD E/e′ ratio correlated significantly with the SLAM (r= -0.409, P=0.0119), although the after-LVAD E/e′ did not (r= -0.249, P=0.1631). After LVAD implantation, the mean SLAM of patients increased in steepness from 7.3 ± 2.44 to 14.7 ± 5.01 cm/s (n=42; P <0.0001) at a mean of 11 months after implantation (range, 5 d-47 mo) (Fig.…”

Section: Demographic Characteristics Of the Lvad Study Populationmentioning

confidence: 94%

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Slope of the Anterior Mitral Valve Leaflet: A New Measurement of Left Ventricular Unloading for Left Ventricular Assist Devices and Systolic Dysfunction

Martinez¹,

Bradley²,

Novak³

et al. 2014

Texas Heart Institute Journal

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Left ventricular assist device (LVAD)-T herapy with an implanted continuous-flow left ventricular assist device (CF-LVAD) has improved survival rates and quality of life in patients with endstage heart failure by increasing cardiac output and decreasing left ventricular (LV) preload.1-3 In non-LVAD-supported patients with heart failure, multiple transthoracic echocardiographic (TTE) methods exist for evaluating LV filling pressures, including chamber dimensions, mitral valve inflow Doppler measurements, pulmonary venous Doppler measurements, and tissue Doppler velocities. [4][5][6] In patients with nonphysiologic unloading of the LV by a CF-LVAD, acquisition and interpretation of the Doppler and echocardiographic images required for many of these accepted methods might be challenging. Even in circumstances in which accurate Doppler evaluation is possible, some studies in CF-LVAD patients have revealed that, although E/e′ ratio decreases after LVAD implantation, it correlates poorly with invasive measurements of pulmonary capillary wedge pressure (PCWP). 7,8 Other guidelines are therefore needed to supplement current knowledge toward evaluating LV unloading and clinical status in CF-LVAD-supported patients.The mitral valve is a fast-moving structure, the motion of which is best detected with the superior temporal resolution of M-mode echocardiography in the parasternal views. 9 In the presence of elevated filling pressures, the anterior mitral leaflet tracing in M-mode displays gradual closure after the peak of the A-wave in cardiac diastole, as compared with brisk closure in patients with normal filling pressures. 9 In extreme cases, this closure process slows to the point where there is a recognizable "B-bump" after atrial contraction, which for more than 40 years has been known to correlate with significantly elevated LV end-diastolic pressure (LVEDP)-greater than 20 mmHg. 10Until now, the slope of the anterior mitral leaflet (SLAM) in end-diastole has never

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Section: Demographic Characteristics Of the Lvad Study Populationsupporting

confidence: 72%

Section: Demographic Characteristics Of the Lvad Study Populationmentioning

confidence: 94%

Slope of the Anterior Mitral Valve Leaflet: A New Measurement of Left Ventricular Unloading for Left Ventricular Assist Devices and Systolic Dysfunction

Martinez¹,

Bradley²,

Novak³

et al. 2014

Texas Heart Institute Journal

View full text Add to dashboard Cite

show abstract

“…In general, incremental rotation speed or fluid replacement may be effective in ameliorating low output during LVAD support. 32 In patients with late-onset RVF, incremental rotation speed did not…”

Section: Mechanisms For Late-onset Rvf After Lvad Implantationmentioning

confidence: 99%

Late-Onset Right Ventricular Failure in Patients With Preoperative Small Left Ventricle After Implantation of Continuous Flow Left Ventricular Assist Device

Imamura

Kinugawa

Kato

et al. 2014

Circ J

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“…A recent study of 63 stable outpatients with normalfunctioning HM II devices noted that efficient LV unloading was associated with a 17% reduction in LV end-diastolic diameter 3 months after LVAD implantation (5.6Ϯ1.1 versus 6.8Ϯ0.9 cm pre-LVAD). 5 Although LV volumes provide a more accurate assessment of LV size, their accurate measurement, unlike LV dimensions, can be challenging from the standard apical view because of the apical inflow cannula and its associated shadowing/attenuation artifact, in addition to echocardiographic dropout at the apex. Because of these limitations, ventricular volumes can be underestimated when assessed by echocardiography.…”

Section: Evaluation Of Ventricular Size and Function By Echocardiogramentioning

confidence: 99%

Imaging for Ventricular Function and Myocardial Recovery on Nonpulsatile Ventricular Assist Devices

et al. 2012

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Echocardiographic Findings in Stable Outpatients with Properly Functioning HeartMate II Left Ventricular Assist Devices

Cited by 51 publications

References 25 publications

Slope of the Anterior Mitral Valve Leaflet: A New Measurement of Left Ventricular Unloading for Left Ventricular Assist Devices and Systolic Dysfunction

Slope of the Anterior Mitral Valve Leaflet: A New Measurement of Left Ventricular Unloading for Left Ventricular Assist Devices and Systolic Dysfunction

Late-Onset Right Ventricular Failure in Patients With Preoperative Small Left Ventricle After Implantation of Continuous Flow Left Ventricular Assist Device

Imaging for Ventricular Function and Myocardial Recovery on Nonpulsatile Ventricular Assist Devices

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