Echocardiographic Findings in Patients With Behçet’s Disease

Bozkurt, Abdi; Akpınar, Onur; Uzun, Soner; Akman, Ayşe; Arslan, Didem; Birand, Ahmet

doi:10.1016/j.amjcard.2005.09.120

Cited by 25 publications

(19 citation statements)

References 22 publications

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“…Our results confirmed the results of others who found impairment of LV diastolic functions in BD patients compared to the controls [35][36][37]. This can be explained as vasculitis affecting the intramural and small coronary arteries which may cause weakening of endocardial and myocardial tissue and replacement by fibrosis due to myocardial ischemia [38].…”

Section: Discussionsupporting

confidence: 94%

Assessment of left ventricular function and aortic elastic properties in patients with Behçet’s disease using conventional and tissue Doppler echocardiography

Hassan

Ebaid

2016

The Egyptian Rheumatologist

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Background: Behc¸et disease (BD) is a multisystemic, chronic inflammatory disorder of unknown etiology with diffuse clinical manifestations including the cardiovascular system.Aim of the work: To assess left ventricular (LV) function and thoracic aorta elastic properties in BD patients using Doppler echocardiography and to correlate echocardiographic findings with disease activity.Patients and methods: The LV functions and thoracic aorta elastic properties were assessed in 30 BD patients and 30 controls using conventional and Tissue Doppler Imaging (TDI) echocardiography. Disease activity was evaluated using Behc¸et's disease current activity form (BDCAF). Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), cholesterol and triglyceride levels were measured.Results: In BD patients, ESR and CRP were significantly elevated while cholesterol and triglycerides were comparable to the levels in the control. In conventional echocardiography, BD patients had significantly higher aortic diastolic diameter (p < 0.05), aortic stiffness index (p < 0.001), isovolumic relaxation time (p < 0.001), flow propagation velocity (FPV) and peak E-wave velocity/FPV (E/FPV) (p < 0.001) than the control group while aortic strain was significantly lower

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Section: Discussionsupporting

confidence: 94%

Assessment of left ventricular function and aortic elastic properties in patients with Behçet’s disease using conventional and tissue Doppler echocardiography

Hassan

Ebaid

2016

The Egyptian Rheumatologist

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“…9,10 Bozkurt et al 10 concluded normal resting and exercise left ventricular functions in patients with BD. Our study has some limitations.…”

Section: Discussionmentioning

confidence: 99%

“…4,5 Pericardial, myocardial, endocardial, and coronary artery complications were documented in patients with BD. 6,7 While some studies suggested that BD does not result in impaired left ventricular diastolic function (LVDF), [8][9][10] others have documented impaired LVDF. [11][12][13][14] One study suggested that the incidence of left ventricular diastolic dysfunction (LVDD) in BD is related to the geographic distribution of patients.…”

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confidence: 99%

Assessment of Left Ventricular Diastolic Function in Egyptian Patients With Behçet’s Disease

et al. 2016

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Objectives: This study aims to evaluate left ventricular diastolic function in Egyptian patients with Behçet's disease using variable echocardiographic parameters by combining both transmitral and tissue Doppler velocities to overcome the occasional false interpretation of preload dependent transmitral parameters and to detect the correlation between various left ventricular diastolic parameters and different disease manifestations. Patients and methods: Forty patients (35 males, 5 females; mean age 31±8 years; range 19 to 52 years) with Behçet's disease and 32 age-and sexmatched healthy controls (26 males, 6 females; mean age 28±6 years; range 19 to 60 years) were enrolled. Left ventricular diastolic function was assessed using an algorithm that combined transmitral and tissue Doppler derived parameters. Results: Mean disease duration of the patients was 7.4±6 years. Left and right ventricular systolic function was normal in both groups. The transmitral E/A was <1 in six patients (15%). There was no difference between patients and controls regarding the other left ventricular diastolic parameters. Compared to patients with an E/A ratio >1, patients with E/A <1 were significantly older and had a longer disease duration (p=0.001 and p<0.001, respectively). All the other echocardiographic parameters in both groups were comparable. Conclusion: Egyptian patients with Behçet's disease have normal left ventricular diastolic function regardless of disease duration and activity.

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“…[4][5][6][7][8] To date, there have been several studies investigating the cardiac functions in BD. [9][10][11][12][13][14] In those studies, conventional echocardiography has been used for the assessment of cardiac function. However, several controversial results were obtained particularly regarding diastolic functions.…”

mentioning

confidence: 99%

“…However, several controversial results were obtained particularly regarding diastolic functions. [9][10][11][12][13][14] Hence, novel methods for more objective estimation of the cardiac functions such as tissue Doppler echocardiography (TDE) or Doppler-derived myocardial performance index (MPI) might be helpful in BD. Such as, MPI, which combines both systolic and diastolic function, 15 ventricular dyssynchrony, which indicates heterogeneity of contraction time between different myocardial segments, may give a better reflection of the global left ventricular (LV) function than conventional echocardiography, though, to our knowledge, these have not been investigated so far.…”

mentioning

confidence: 99%